Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides.

dc.contributor.authorNag, Men_US
dc.contributor.authorNandy, Nen_US
dc.date.accessioned2009-05-28T14:41:32Z
dc.date.available2009-05-28T14:41:32Z
dc.date.issued2001-08-23en_US
dc.description.abstractOrganophosphate (OP) pesticides, monocrotophos (MCP), dichlorvos (DDVP) and phosphamidon significantly inhibit both MAO-A and MAO-B activities in rat brain mitochondria. The inhibition of MAO-A by MCP is reversible whereas the inhibition by DDVP and phosphamidon is irreversible. MAO-B is inhibited irreversibly by all these organophosphates suggesting that the mechanism of action of OP pesticides is through phosphorylation of serine residue present in active centre of MAO.en_US
dc.description.affiliationIndian Institute of Chemical Biology, Jadavpur, Calcutta, India. iichbio@giasc101.vsnl.net.inen_US
dc.identifier.citationNag M, Nandy N. Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides. Indian Journal of Experimental Biology. 2001 Aug; 39(8): 802-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/61036
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBenzylamines --metabolismen_US
dc.subject.meshBrain --enzymologyen_US
dc.subject.meshInsecticides --metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshMitochondria --enzymologyen_US
dc.subject.meshMonoamine Oxidase --metabolismen_US
dc.subject.meshOrganophosphorus Compoundsen_US
dc.subject.meshOxidation-Reductionen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshSerotonin --metabolismen_US
dc.titleSerotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides.en_US
dc.typeJournal Articleen_US
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