Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides.
dc.contributor.author | Nag, M | en_US |
dc.contributor.author | Nandy, N | en_US |
dc.date.accessioned | 2009-05-28T14:41:32Z | |
dc.date.available | 2009-05-28T14:41:32Z | |
dc.date.issued | 2001-08-23 | en_US |
dc.description.abstract | Organophosphate (OP) pesticides, monocrotophos (MCP), dichlorvos (DDVP) and phosphamidon significantly inhibit both MAO-A and MAO-B activities in rat brain mitochondria. The inhibition of MAO-A by MCP is reversible whereas the inhibition by DDVP and phosphamidon is irreversible. MAO-B is inhibited irreversibly by all these organophosphates suggesting that the mechanism of action of OP pesticides is through phosphorylation of serine residue present in active centre of MAO. | en_US |
dc.description.affiliation | Indian Institute of Chemical Biology, Jadavpur, Calcutta, India. iichbio@giasc101.vsnl.net.in | en_US |
dc.identifier.citation | Nag M, Nandy N. Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides. Indian Journal of Experimental Biology. 2001 Aug; 39(8): 802-6 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/61036 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.asp | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Benzylamines --metabolism | en_US |
dc.subject.mesh | Brain --enzymology | en_US |
dc.subject.mesh | Insecticides --metabolism | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Mitochondria --enzymology | en_US |
dc.subject.mesh | Monoamine Oxidase --metabolism | en_US |
dc.subject.mesh | Organophosphorus Compounds | en_US |
dc.subject.mesh | Oxidation-Reduction | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Rats, Wistar | en_US |
dc.subject.mesh | Serotonin --metabolism | en_US |
dc.title | Serotonin and benzylamine oxidation by type A and type B MAO of rat brain in presence of organophosphate pesticides. | en_US |
dc.type | Journal Article | en_US |
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