Sero-prevalence of Rubella Antibodies in Pregnant Women with Bad Obstetric History Attending A Rural Tertiary Care Hospital in West Bengal, India

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dc.contributor.authorChattopadhyay, Sen_US
dc.contributor.authorBiswas, Ten_US
dc.contributor.authorChakraborty, Ben_US
dc.contributor.authorMukherjee, Ten_US
dc.contributor.authorGhosh, Pen_US
dc.contributor.authorMondal, Ren_US
dc.date.accessioned2019-11-04T04:58:23Z
dc.date.available2019-11-04T04:58:23Z
dc.date.issued2019-07
dc.description.abstractBackground: Rubella infection in pregnant mothers is of great concern as it acts as a teratogen causing abortions, still births, intra-uterine foetal deaths and multiple birth defects. In India, rubella causes significant bad obstetric pregnancy outcome including congenital deformities due to lack of proper surveillance and immunization coverage with rubella vaccination. Aim: To determine Sero-prevalence of rubella IgM and IgG antibodies in Bad Obstetric History (BOH) pregnant women in Tertiary Rural Medical College in Eastern India. Materials and Methods: Cross sectional study was conducted from 1st January 2017 to 31st March 2017 on sera of 100 antenatal mothers with bad obstetric history aged between 20-40 years of age group with pregnancy of ≥18 wks. Rubella IgM and IgG antibodies were assessed by ELISA. Statistical Analysis: Percentage, proportions and ᵡ2 test were applied. Results: Eleven per cent (11%) sero-prevalence for IgM antibodies and 54% for IgG antibodies was observed with maximum sero-positivity among 20-25 years mothers. Repeated abortions were the commonest pregnancy outcome. Conclusion: All antenatal cases should be routinely screened for rubella, so that early diagnosis will help in proper management and foetal outcome and strong recommendation for universal coverage of MMR in early age group of children.en_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, Burdwan Medical College and Hospital, Purba Barddhaman – 713104, West Bengal, India; dr.saswatichattopadhyay@gmail.comen_US
dc.identifier.affiliationsAssociate Professor, Department of Microbiology, IPGME&R, Kolkata – 700020, West Bengal, India; dr.tanusribiswas@rediffmail.comen_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, R. G. Kar Medical College, Kolkata – 700004, West Bengal, India; bipasa_doc@yahoo.co.inen_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, Burdwan Medical College and Hospital, Purba Barddhaman – 713104, West Bengal, India; tmukherjee2008@gmail.comen_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, Burdwan Medical College and Hospital, Purba Barddhaman – 713104, West Bengal, India; purbashaghosh02@gmail.comen_US
dc.identifier.affiliationsAssistant Professor, Department of Community Medicine, Burdwan Medical College, Purba Bardhaman 713104, West Bengal, India; rastonmondal@rediffmail.comen_US
dc.identifier.citationChattopadhyay S, Biswas T, Chakraborty B, Mukherjee T, Ghosh P, Mondal R. Sero-prevalence of Rubella Antibodies in Pregnant Women with Bad Obstetric History Attending A Rural Tertiary Care Hospital in West Bengal, India. International Journal of Medical and Dental Sciences. 2019 Jul; 8(2): 1749-1753en_US
dc.identifier.issn2454-8952
dc.identifier.issn2320-1118
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/183631
dc.languageenen_US
dc.publisherDr. J.S. Sodhi Memorial Educational Societyen_US
dc.relation.issuenumber2en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.18311/ijmds/2019/23313en_US
dc.subjectAntenatal Mothersen_US
dc.subjectBad Obstetric Historyen_US
dc.subjectIgM & IgG Antibodiesen_US
dc.subjectRecurrent Abortionen_US
dc.subjectRubellaen_US
dc.subjectMedical Microbiologyen_US
dc.titleSero-prevalence of Rubella Antibodies in Pregnant Women with Bad Obstetric History Attending A Rural Tertiary Care Hospital in West Bengal, Indiaen_US
dc.typeJournal Articleen_US
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