Hypertrophic cardiomyopathy: Part 1 - Introduction, pathology and pathophysiology.

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dc.contributor.authorVarma, Praveen Kerala
dc.contributor.authorNeema, Praveen Kumar
dc.date.accessioned2014-04-29T05:15:15Z
dc.date.available2014-04-29T05:15:15Z
dc.date.issued2014-04
dc.description.abstractHypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular disease with many genotype and phenotype variations. Earlier terminologies, hypertrophic obstructive cardiomyopathy and idiopathic hypertrophic sub‑aortic stenosis are no longer used to describe this entity. Patients present with or without left ventricular outflow tract (LVOT) obstruction. Resting or provocative LVOT obstruction occurs in 70% of patients and is the most common cause of heart failure. The pathology and pathophysiology of HCM includes hypertrophy of the left ventricle with or without right ventricular hypertrophy, systolic anterior motion of mitral valve, dynamic and mechanical LVOT obstruction, mitral regurgitation, diastolic dysfunction, myocardial ischemia, and fibrosis. Thorough understanding of pathology and pathophysiology is important for anesthetic and surgical management.en_US
dc.identifier.citationVarma Praveen Kerala, Neema Praveen Kumar. Hypertrophic cardiomyopathy: Part 1 - Introduction, pathology and pathophysiology. Annals of Cardiac Anaesthesia. 2014 Apr; 17(2): 118-124.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/150309
dc.language.isoenen_US
dc.source.urihttps://www.annals.in/article.asp?issn=0971-9784;year=2014;volume=17;issue=2;spage=118;epage=124;aulast=Varmaen_US
dc.subjectHeart failureen_US
dc.subjectHypertrophic cardiomyopathyen_US
dc.subjectLeft ventricular outflow obstructionen_US
dc.subjectMitral regurgitationen_US
dc.subjectSystolic anterior motionen_US
dc.subject.meshCardiomyopathy, Hypertrophic --genetics
dc.subject.meshCardiomyopathy, Hypertrophic --pathology
dc.subject.meshCardiomyopathy, Hypertrophic --physiopathology
dc.subject.meshCardiomyopathy, Hypertrophic --physiology
dc.subject.meshHumans
dc.subject.meshMitral Valve Insufficiency
dc.subject.meshSystole --physiology
dc.subject.meshVentricular Outflow Obstruction
dc.titleHypertrophic cardiomyopathy: Part 1 - Introduction, pathology and pathophysiology.en_US
dc.typeArticleen_US
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