Greater Auricular and Ulnar Nerve Damage in Leprosy: Clinical and Electrophysiological Comparison

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dc.contributor.authorGupta, Pen_US
dc.contributor.authorMainra, Aen_US
dc.contributor.authorSharma, Sen_US
dc.contributor.authorShanker, Ven_US
dc.date.accessioned2020-04-10T01:22:15Z
dc.date.available2020-04-10T01:22:15Z
dc.date.issued2019-06
dc.description.abstractClinically leprosy can have varied presentations ranging from an insignificant skin lesion to extensive disease causing profound disability and disfigurement by damaging peripheral nerves, eyes, bones and other tissues. Peripheral nerve involvement occurs sooner or later in the disease course leading to gross deformities and disabilities. Deformities in leprosy are secondary to nerve damage. However, by the time it clinically manifests, the nerve damage may already be quite advanced. If the preclinical damage is detected early, it can be prevented largely. The study was conducted in the Department of Dermatology, Venereology & Leprosy and Department of Neurology, Indira Gandhi Medical College, Shimla over a period of one year. This electrophysiological study included 20 patients with clinical manifestations of leprosy. 15/20 (75%) belonged to BL/LL types. 18 patients (90%) were multibacillary and 2(10%) were paucibacillary types. Nerve conduction velocity, amplitude and latency of greater auricular and ulnar sensory nerves were done. We found reduced conduction velocities, changes in latency and amplitude in the affected nerves. Ulnar nerve was more commonly involved than the greater auricular nerve. Out of 32 thickened ulnar nerves clinically, only 12 nerves (37.5%) had nerve function impairment. Two non-thickened nerves (2.5%) also had sensory impairment; in contrast 24 thickened nerves had normal functions. Thus, Nerve Conduction Studies can help in detection of early nerve impairment in some cases which otherwise may not be detected clinically. While overall these investigations appear to have limited value in diagnosis of disease and their prognostic value in monitoring the disease progression/response to intervention should be determined by follow-up studies. Valid conclusions with wider application value can only be drawn after carrying out follow up studies on a significant number of leprosy cases.en_US
dc.identifier.affiliationsDr Priyanka Gupta, MD (Dermatology, Venereology and Leprology)en_US
dc.identifier.affiliationsDr Amit Mainra, MS (Surgery), Department of Surgeryen_US
dc.identifier.affiliationsDr Sudhir Sharma, MD, DM, Associate Professor, Department of Neurologyen_US
dc.identifier.affiliationsDr Vinay Shanker, Ex-Professor and Head, Department of Dermatology, Venereology and Leprosy Indira Gandhi Medical College (IGMC) Shimla, H.P. –171011, Indiaen_US
dc.identifier.citationGupta P, Mainra A, Sharma S, Shanker V. Greater Auricular and Ulnar Nerve Damage in Leprosy: Clinical and Electrophysiological Comparison. Indian Journal of Leprosy. 2019 Jun; 91(2): 105-116en_US
dc.identifier.issn0254-9395
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/195039
dc.languageenen_US
dc.publisherHind Kusht Nivaran Sangh (Indian Leprosy Association)en_US
dc.relation.issuenumber2en_US
dc.relation.volume91en_US
dc.source.urihttps://www.ijl.org.in/apr-jun-2019.htmlen_US
dc.subjectLeprosyen_US
dc.subjectElectrophysiologyen_US
dc.subjectNerve Conductionen_US
dc.subjectNeuropathyen_US
dc.titleGreater Auricular and Ulnar Nerve Damage in Leprosy: Clinical and Electrophysiological Comparisonen_US
dc.typeJournal Articleen_US
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