Impaired Renal Function is Associated with Severe Coronary Artery Disease in Chronic Stable Angina Patients.

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dc.contributor.authorSaha, J N
dc.contributor.authorMajumder, A A S
dc.contributor.authorChowdhury, N A
dc.contributor.authorUllah, M
dc.contributor.authorAzam, M G
dc.contributor.authorKarmoker, K K
dc.contributor.authorIslam, M J
dc.contributor.authorDas, P R
dc.contributor.authorIslam, M S
dc.contributor.authorMamunuzzaman, M
dc.contributor.authorBiswas, P
dc.contributor.authorRahman, M A
dc.date.accessioned2015-12-16T09:44:44Z
dc.date.available2015-12-16T09:44:44Z
dc.date.issued2014
dc.description.abstractBackground: Cardiovascular disease is the leading cause of morbidity and mortality in renal impaired patients. Many of the patients of chronic kidney disease die of cardiovascular disease before requiring dialysis. Cardiovascular disease in renal impaired patient is potentially preventable and treatable. The aim of this study was to evaluate the association between renal impairment and coronary artery disease severity in chronic stable angina patients. Methods: 110 patients with chronic stable angina who got admitted for coronary angiography were included in the study. They were divided into impaired renal function group (with estimated glomerular filtration rate [eGFR] <90 ml/min/1.73m2) and normal renal function group (eGFR e” 90 ml/min/1.73m2) on the basis of eGFR. The severity of the CAD was assessed by angiographic Vessel score and Gensini score. Results: Mean Gensini score was significantly high in impaired renal function group (42.30±24.9 vs 25.65±17.9, p <0.05). There was significant negative correlation between eGFR and vessel score (r=-0.30, p <0.05) and between eGFR and Gensini score (r =-0.65, P <0.05). In multivariate logistic regression analysis, after adjustment of factors eGFR remain independent predictors of severe CAD (P=0.002, OR -5.73). Conclusion: Impaired renal function, assessed by eGFR is associated with angiographic severe coronary artery disease in chronic stable angina patients and this association is independent of conventional cardiovascular risk factors.en_US
dc.identifier.citationSaha J N, Majumder A A S, Chowdhury N A, Ullah M, Azam M G, Karmoker K K, Islam M J, Das P R, Islam M S Mamunuzzaman M, Biswas P, Rahman M A. Impaired Renal Function is Associated with Severe Coronary Artery Disease in Chronic Stable Angina Patients. Cardiovascular Journal. 2014; 7(1): 17-23.en_US
dc.identifier.issn2071-0917
dc.identifier.issn2309-6357
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/168313
dc.language.isoenen_US
dc.source.urihttps://banglajol.info/index.php/CARDIO/article/view/20796en_US
dc.subjectRenal Impairmenten_US
dc.subjectCoronary Artery Diseaseen_US
dc.titleImpaired Renal Function is Associated with Severe Coronary Artery Disease in Chronic Stable Angina Patients.en_US
dc.typeArticleen_US
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