Effect of early enteral feeding on recovery profile in mild acute pancreatitis

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dc.contributor.authorChandran, Kailashen_US
dc.contributor.authorMammen, Sam Christyen_US
dc.date.accessioned2020-11-18T10:04:35Z
dc.date.available2020-11-18T10:04:35Z
dc.date.issued2020-06
dc.description.abstractBackground: Acute pancreatitis is a pestilent disease with severity ranging from mild and self-limiting to a rapidly progressive illness leading to multi organ failure. Mild acute pancreatitis is inflammation of the pancreas with minimal remote organ involvement. Since the disturbance in the homeostasis is minimal, the treatment aims at supporting the native reparative processes of the body. One of the main supportive mechanisms is adequate nutritional supplementation. Gut barrier damage in the early phase of acute pancreatitis accounts for the bacterial translocation, initiation of sepsis, infected pancreatic necrosis and SIRS. Aim of the study was to determine the feasibility, advantages and disadvantages of early enteral nutrition in mild acute pancreatitis.Methods: 40 patients taken consecutively from units which start enteral feeds before 48 hours (study group) were compared against 40 patients taken consecutively from units where patients will be kept fasting for 48 hours (control group) to determine whether early enteral feeding is better in determining the recovery in terms of duration of hospital stay, reduction in abdominal symptoms and use of analgesics.Results: There was significant reduction in the duration of hospital stay (p=0.011), intensity and duration of abdominal pain, need for analgesics, and risk of oral food intolerance in the study group.Conclusions: Patients with mild acute pancreatitis can safely be started on early enteral feeds. It reduces gastro intestinal adverse effects, abdominal pain and need for analgesics and improves oral food tolerance causing shorter hospital stay.en_US
dc.identifier.affiliationsDepartment of General Surgery, Government Medical College, Kottayam, Kerala, Indiaen_US
dc.identifier.citationChandran Kailash, Mammen Sam Christy. Effect of early enteral feeding on recovery profile in mild acute pancreatitis. International Surgery Journal. 2020 Jun; 7(6): 1969-1976en_US
dc.identifier.issn2349-3305
dc.identifier.issn2349-2902
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/212962
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber6en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-2902.isj20202414en_US
dc.subjectAbdominal painen_US
dc.subjectAnalgesicsen_US
dc.subjectEarly enteral feedsen_US
dc.subjectMild acute pancreatitisen_US
dc.titleEffect of early enteral feeding on recovery profile in mild acute pancreatitisen_US
dc.typeJournal Articleen_US
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