Experimental hyperthyroidism-induced oxidative stress and impairment of antioxidant defence system in rat testis.

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dc.contributor.authorSahoo, Dipak Ken_US
dc.contributor.authorRoy, Anitaen_US
dc.contributor.authorBhanja, Shravanien_US
dc.contributor.authorChainy, G B Nen_US
dc.date.accessioned2009-05-28T16:14:49Z
dc.date.available2009-05-28T16:14:49Z
dc.date.issued2005-11-30en_US
dc.description.abstractShort-term hyperthyroidism, induced by daily administration of T3 (20 microg/100g body weight) for one, three, and five days consecutively, modulates oxidative stress and antioxidant defence parameters in mitochondrial and postmitochondrial fractions of testis in adult rats. Alteration in antioxidant defences along with oxidative stress parameters in testis by thyroid hormone was found to be associated with a decline in the number of sperms and disturbances in histoarchitecture of seminiferous tubules in the testes; the results indicated that induced hyperthyroid state altered testicular physiology by influencing antioxidant defence system of testes.en_US
dc.description.affiliationDepartment of Biotechnology, Utkal University, Bhubaneswar 7510 04, India.en_US
dc.identifier.citationSahoo DK, Roy A, Bhanja S, Chainy GB. Experimental hyperthyroidism-induced oxidative stress and impairment of antioxidant defence system in rat testis. Indian Journal of Experimental Biology. 2005 Nov; 43(11): 1058-67en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62992
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntioxidants --metabolismen_US
dc.subject.meshBlotting, Westernen_US
dc.subject.meshBody Weighten_US
dc.subject.meshCarbon --chemistryen_US
dc.subject.meshCatalase --chemistryen_US
dc.subject.meshDisease Models, Animalen_US
dc.subject.meshHyperthyroidism --pathologyen_US
dc.subject.meshLipid Peroxidationen_US
dc.subject.meshMaleen_US
dc.subject.meshOxidants --chemistryen_US
dc.subject.meshOxidative Stressen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshReactive Oxygen Speciesen_US
dc.subject.meshSuperoxide Dismutase --metabolismen_US
dc.subject.meshTestis --metabolismen_US
dc.subject.meshThiobarbituric Acid Reactive Substancesen_US
dc.subject.meshTime Factorsen_US
dc.subject.meshTissue Distributionen_US
dc.titleExperimental hyperthyroidism-induced oxidative stress and impairment of antioxidant defence system in rat testis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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