Effect of catechin on intestinal lipid metabolism.

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dc.contributor.authorValsa, A Ken_US
dc.contributor.authorAsha, S Ken_US
dc.contributor.authorVijayalakshmi, N Ren_US
dc.date.accessioned1998-04-04en_US
dc.date.accessioned2009-06-01T06:48:08Z
dc.date.available1998-04-04en_US
dc.date.available2009-06-01T06:48:08Z
dc.date.issued1998-04-04en_US
dc.description.abstractOn analysing the effect of catechin on intestinal lipid metabolism, an increase in the concentration of cholesterol in the duodenum and jejunum was observed along with an increase in the HMGCoA reductase activity. In the in vitro experiments also it was found that cholesterol and free fatty acid (FFA) levels were increased in these two regions. Binding of catechin with cholesterol in the lumen, reduces the availability of cholesterol for absorption which may in turn stimulate cholesterol biosynthesis and a rise in the HMGCoA reductase activity. These alterations produced by catechin may also be related to the degradation of cholesterol to bile acids, as endogenous cholesterol is the preferred substrate for bile acid synthesis.en_US
dc.description.affiliationDepartment of Biochemistry, University of Kerala, Kariavattom, Trivandrum.en_US
dc.identifier.citationValsa AK, Asha SK, Vijayalakshmi NR. Effect of catechin on intestinal lipid metabolism. Indian Journal of Physiology and Pharmacology. 1998 Apr; 42(2): 286-90en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/107666
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCarbon Radioisotopes --diagnostic useen_US
dc.subject.meshCatechin --pharmacologyen_US
dc.subject.meshCholesterol --metabolismen_US
dc.subject.meshGlucose --metabolismen_US
dc.subject.meshHydroxymethylglutaryl CoA Reductases --metabolismen_US
dc.subject.meshIntestines --drug effectsen_US
dc.subject.meshLipid Metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshPhospholipids --metabolismen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Sprague-Dawleyen_US
dc.subject.meshTriglycerides --metabolismen_US
dc.titleEffect of catechin on intestinal lipid metabolism.en_US
dc.typeJournal Articleen_US
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