Predictive efficacy of Framingham's risk score in Indian scenario--a retrospective case-control study.

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dc.contributor.authorGuha, Sen_US
dc.contributor.authorBasu, A Ken_US
dc.contributor.authorPal, S Ken_US
dc.contributor.authorChatterjee, Nen_US
dc.contributor.authorGuha, Sharmilaen_US
dc.contributor.authorDeb, P Ken_US
dc.date.accessioned2004-10-13en_US
dc.date.accessioned2009-05-31T06:28:35Z
dc.date.available2004-10-13en_US
dc.date.available2009-05-31T06:28:35Z
dc.date.issued2004-10-13en_US
dc.description.abstractTo assess the predictive ability of Framingham's risk score in primary prevention in our population, 252 cases and 212 age and sex matched controls were taken up for study. Those patients, who were presenting for the first time with acute coronarysyndrome (ACS) and who did not have any prior manifestations of coronary artery disease (CAD) and whose medical records were available formed the patient group. Framingham's risk score was calculated and the corresponding 10 years risk was assessed in each of them. The patients and controls were divided into two groups--diabetic and non-diabetic. Depending on the 10 years risk, they were further grouped into high risk (10 years risk > 20%), moderately high risk (10 years risk 10 to 20%) and low risk (10 years risk less than 10%). Results were compared and statistically analysed. In the diabetic patients with ACS 14% would have qualified as high risk, 33% as moderately high risk and 53% as low risk whereas in diabetic patients without any manifestation of CAD the distribution was 4% in the high risk, 54% in the moderately high risk and 42% in the low risk. In the non-diabetic subjects, amongst the patients of ACS, 20% would have been in high risk, 39% in moderately high risk and 41% in the low risk. The corresponding figures in the non-diabetic control subjects were 10% in high risk, 22% in the moderately high risk and 68% in the low risk. In the non-diabetic subjects, the mean risk was significantly more in patients than in controls (14.15% versus 8.61%, p <0.01). However, in the diabetic patients there was no significant difference in the mean projected risk between patients with ACS and patients without any manifestation of CAD (11.37% versus 10.41%, p>0.05).en_US
dc.description.affiliationDepartment of Medicine, Medical College, Kolkata 700073.en_US
dc.identifier.citationGuha S, Basu AK, Pal SK, Chatterjee N, Guha S, Deb PK. Predictive efficacy of Framingham's risk score in Indian scenario--a retrospective case-control study. Journal of the Indian Medical Association. 2004 Oct; 102(10): 568, 570, 584 passimen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/96064
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAgeden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshCoronary Artery Disease --complicationsen_US
dc.subject.meshCoronary Disease --complicationsen_US
dc.subject.meshDiabetes Complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.titlePredictive efficacy of Framingham's risk score in Indian scenario--a retrospective case-control study.en_US
dc.typeJournal Articleen_US
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