Effectiveness of Midazolam Compared to Diazepam and Placebo For Reducing Anxiety after Premedication at Sylhet Women’s Medical College

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Date
2020-03
Journal Title
Journal ISSN
Volume Title
Publisher
Ibn Sina Academy of Medieval Medicine & Sciences
Abstract
Introduction: Anxiolytic premedication is debated most of thetime in the outpatient surgical community. The management ofanxiety reducing medications may be considered unnecessaryby anesthesiologists when anxiety rates are small inoutpatients with minor operations. Thanks to its rapid onsetand short halflife, intravenous (IV) midazolam is the mostwidely used premedicant in ambulatory environments, but itspersistent effects in the prompt postoperative period may leadto postoperative sedation, as well as delayed recovery anddischarge readiness after brief ambulatory surgery.Objective: This research is carried out specifically to checkwhether the use of the medicine for preanesthesia midazolamquantifiably decreases pain as opposed to having nopreanesthesia drug (placebo) or diazepam prior to medicalprocedures.Method: The examination's inclusion requirements arepatients aged between 18 and 68 years scheduled for electivesurgery or diagnostic procedures involving anesthesia. Aninterventional (clinical trial) study with 160 patients scheduledfor surgical or diagnostic procedures involving anesthesiatechniques was performed at a neighbourhood emergencyclinic called Sylhet Women’s Medical College located in Sylhet,Bangladesh. Research length from Aug 2018 to Aug 2019.Results: After multiple investigations of knowledge andanalysis it was discovered that diazepam with little or nosymptoms placed ahead of midazolam and placebo.Conclusion: It can be clearly inferred that in case of adecrease in anxiety, diazepam ranks first compared tomidazolam or placebo.
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Keywords
Premedication, Midazolam, Placebo, Anesthesia, Diazepam.
Citation
Ehsan Ali, Md Shahnewaz Chowdhury, Roy Tanmoy Deb, Shemul Sujoy Das. Effectiveness of Midazolam Compared to Diazepam and Placebo For Reducing Anxiety after Premedication at Sylhet Women’s Medical College. International Journal of Medical Research Professionals. 2020 Mar; 6(2): 78-81