Seroprevalence of Immunoglobulin G antibodies to SARS-COV-2 in asymptomatic healthcare workers in a South Indian Tertiary care NephroUrology Center
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Date
2020-05
Journal Title
Journal ISSN
Volume Title
Publisher
Medical Council of India
Abstract
SARS-CoV-2 (Severe acute respiratory syndrome corona virus 2) Seroprevalence studies are being conducted all over theworld to identify the level of exposure to the virus, in different groups of population. These include laboratory basedserological tests to detect the presence of antibodies in response to an exposure/infection with the SARS-CoV-2 virus. The aimof the study was to know the prevalence of SARS-CoV-2 IgG Antibodies in Health Care Workers (HCWs) of our hospital. Across-sectional serological study was conducted in a tertiary care center for Nephrourology in Bangalore, Karnataka, India. TheHCWs of the hospital, of age group 20 to 60 were included in the study and were tested for the presence ofSARS-CoV-2–specific IgG antibodies by Luminescence Immuo Assay method (CLIA). Prevalence was calculated,significance among the subgroups was analyzed using chi-square test and p value. 95 HCWs underwent testing, 6 werepositive for IgG antibodies, with a Sero-prevalence rate of 6.3%. There was no significant difference in prevalence ratebetween male and female, and also between different age groups. It was concluded that serological studies to detectSARS-CoV-2–specific antibodies in HCWs might be helpful to detect the immune status of HCWs. Routine application ofthese tests in HCWs would aid in work stratification of HCWs in managing the covid 19 pandemic.
Description
Keywords
SARS-CoV-2, Corona Virus, antibodies, Health Care Workers
Citation
N S Madhura, R Kowsalya, K M Mythri, N. Shashikala, S Mythri. Seroprevalence of Immunoglobulin G antibodies to SARS-COV-2 in asymptomatic healthcare workers in a South Indian Tertiary care NephroUrology Center. International Journal of Interdisciplinary and Multidisciplinary Studies. 2020 May; 7(2): 92-96