A Follow up Study Among Patients on Opioid Substitution Therapy (OST) in Terms of Relapse Rate, Factors Affecting Relapse Rate and HCV Incidence

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dc.contributor.authorBala, Neeruen_US
dc.contributor.authorNaib, Gauraven_US
dc.contributor.authorSingh, Manjiten_US
dc.contributor.authorKaur, Manmeeten_US
dc.contributor.authorSingh, Amarbirpalen_US
dc.contributor.authorKaur, Sumanjeeten_US
dc.date.accessioned2023-07-21T11:26:30Z
dc.date.available2023-07-21T11:26:30Z
dc.date.issued2023-06
dc.description.abstractBackground: Many countries are facing a serious problem with opioid dependence. Opioid Substitution Therapy (OST) is prescribed to dependent opioid users to diminish the use and effects of illicitly acquired opioids. The high relapse rate has been affecting the effectiveness of anti-drug work all over the world.Material & Methods:In this study, 200 patients were taken by simple random sampling technique. 100 patient on Buprenorphine substitution therapy and 100 on Methadone maintenance treatment were studied. Patients diagnosed as cases of Opioid dependence as per ICD-10 were selected within the first 3 months and followed up to 1 year at 3, 6 and 9 months. The study was conducted after approval from the institutional ethics and thesis committee. A 14-item questionnaire based on a four-point scale describing the number of times certain events had occurred in the previous week for relapse was used to find factors affecting relapse.Results:The relapse rate among patients in the BPN group at 3, 6 and 9 months relapse was 29.33%, 20.34% and 19.51% while in the Methadone group, it was 24.05%, 15.87% and 12% respectively. The overall HCV Incidence was 75% among patients on Opioid Substitution Therapy. Conclusion:The findings of the study highlight the role of multiple determinants in opioid dependence and relapse. The obtained results showed that HCV infection was an alarming problem among IV opiate drug users in Punjab.en_US
dc.identifier.affiliationsProfessor & Head, Department of Psychiatry, GMC, Amritsar, Punjab, India. Email: jpneeru15@gmail.com, Orcid ID: 0000-0002-8526-953Xen_US
dc.identifier.affiliationsJunior Resident, Department of Psychiatry, GMC, Amritsar, Punjab, India. Email: gauravnaib@yahoo.co.in Orcid ID: 0000-0002-5499-8609en_US
dc.identifier.affiliationsAssociate Professor, Department of Psychiatry, GMC, Amritsar, Punjab, India. Email: manjitsingh212@gmail.com Orcid ID: 0000-0003-3869-9462en_US
dc.identifier.affiliationsSenior Resident, Department of Psychiatry, GMC, Amritsar, Punjab, India. Email: manmeetsidhu782@gmail.com Orcid ID: 0000-0001-6744-1095en_US
dc.identifier.affiliationsSenior Resident, Department of Psychiatry, GMC, Amritsar, Punjab, India. Email: dramarsandhu14@gmail.com Orcid ID: 0000-0003-4963-4197en_US
dc.identifier.affiliationsAssistant Professor, Department of Psychiatry, GMC, Amritsar, Punjab, India. Email: dr.suman@hotmail.com Orcid ID: 0000-0002-2775-7471en_US
dc.identifier.citationBala Neeru, Naib Gaurav, Singh Manjit, Kaur Manmeet, Singh Amarbirpal, Kaur Sumanjeet. A Follow up Study Among Patients on Opioid Substitution Therapy (OST) in Terms of Relapse Rate, Factors Affecting Relapse Rate and HCV Incidence. Annals of International Medical and Dental Research. 2023 Jun; 9(3): 243-248en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220172
dc.languageenen_US
dc.publisherScholars Publisheren_US
dc.relation.issuenumber3en_US
dc.relation.volume9en_US
dc.source.urihttps://doi.org/10.53339/aimdr.2023.9.3.29en_US
dc.subjectOSTen_US
dc.subjectRelapseen_US
dc.subjectHCVen_US
dc.subjectOpioid.en_US
dc.titleA Follow up Study Among Patients on Opioid Substitution Therapy (OST) in Terms of Relapse Rate, Factors Affecting Relapse Rate and HCV Incidenceen_US
dc.typeJournal Articleen_US
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