In vivo effect of whole grain flour of finger millet (Eleusine coracana) and kodo millet (Paspalum scrobiculatum) on rat dermal wound healing.

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dc.contributor.authorHegde, Prashant Sen_US
dc.contributor.authorAnitha, Ben_US
dc.contributor.authorChandra, T Sen_US
dc.date.accessioned2009-05-28T15:43:09Z
dc.date.available2009-05-28T15:43:09Z
dc.date.issued2005-03-09en_US
dc.description.abstractInfluence of finger millet and kodo millet on rat dermal wound healing was assessed by making a 4 cm2 (2 x 2 cm) excision wound on the shaven back of rats under ether anesthesia. Finger millet or kodo millet flour (300 mg) as aqueous paste was applied topically once daily for 16 days. The granulation tissue formed on day 4, 8 and 12 was used to estimate some biochemical parameters like protein, DNA, collagen and lipid peroxides. There was significant increase in protein and collagen contents and decrease in lipid peroxides. Biophysical parameters like rate of contraction and number of days for epithelialization were also studied. Rate of contraction was 88-90% in kodo millet and finger millet treated rats in comparison to 75% in untreated rats. The number of days for complete closure of wounds was lower for finger millet (13 days) and kodo millet (14 days) treated rats in comparison to untreated (16 days) rats. The results implicate a possible therapeutical role for finger millet and kodo millet in accelerating the process of wound healing.en_US
dc.description.affiliationDepartment of Biotechnology, Indian Institute of Technology Madras, Chennai 600 036, India.en_US
dc.identifier.citationHegde PS, Anitha B, Chandra TS. In vivo effect of whole grain flour of finger millet (Eleusine coracana) and kodo millet (Paspalum scrobiculatum) on rat dermal wound healing. Indian Journal of Experimental Biology. 2005 Mar; 43(3): 254-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62327
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCollagen --metabolismen_US
dc.subject.meshDNA --metabolismen_US
dc.subject.meshEleusine --metabolismen_US
dc.subject.meshEpithelium --drug effectsen_US
dc.subject.meshFlouren_US
dc.subject.meshLipid Peroxidationen_US
dc.subject.meshMaleen_US
dc.subject.meshPaspalum --metabolismen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshSkin --drug effectsen_US
dc.subject.meshTime Factorsen_US
dc.subject.meshWound Healingen_US
dc.titleIn vivo effect of whole grain flour of finger millet (Eleusine coracana) and kodo millet (Paspalum scrobiculatum) on rat dermal wound healing.en_US
dc.typeJournal Articleen_US
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