Effect of aspirin on isoproterenol induced changes in lipid metabolism in rats.

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dc.contributor.authorManjula, T Sen_US
dc.contributor.authorDevi, C Sen_US
dc.date.accessioned1993-02-01en_US
dc.date.accessioned2009-05-27T08:56:41Z
dc.date.available1993-02-01en_US
dc.date.available2009-05-27T08:56:41Z
dc.date.issued1993-02-01en_US
dc.description.abstractThe effect of aspirin on isoproterenol induced changes in lipid metabolism in rats was studied. Aspirin (1.2 mg/100 g/day) was administered orally for a period of 60 days along with/without isoproterenol (20 mg/100g sc twice at a time interval of 24 h for 2 days). Isoproterenol treated rats showed an increase in the levels of heart cholesterol, triglycerides and free fatty acids. The activity of cholesterol ester synthetase CES was increased significantly with concomitant increase in heart lipid peroxide levels in isoproterenol treatment. Aspirin treatment could restore the enzyme activity to near normal and also reduce the level of lipid peroxides. The lipid changes were minimum in rats treated with aspirin and isoproterenol.en_US
dc.description.affiliationDepartment of Biochemistry, University of Madras.en_US
dc.identifier.citationManjula TS, Devi CS. Effect of aspirin on isoproterenol induced changes in lipid metabolism in rats. Indian Journal of Medical Research. 1993 Feb; 98(): 30-3en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/26156
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAspirin --administration & dosageen_US
dc.subject.meshCholesterol --metabolismen_US
dc.subject.meshFatty Acids, Nonesterified --metabolismen_US
dc.subject.meshHeart --drug effectsen_US
dc.subject.meshIsoproterenol --administration & dosageen_US
dc.subject.meshLipid Metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshMyocardium --enzymologyen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshSterol Esterase --metabolismen_US
dc.subject.meshTriglycerides --metabolismen_US
dc.titleEffect of aspirin on isoproterenol induced changes in lipid metabolism in rats.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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