Seroprevalence & Risk Factors of Hepatitis B Surface Antigen among Pregnant Women Attending a Tertiary Care Hospital of Southern Rajasthan, India

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dc.contributor.authorSharma, Meghaen_US
dc.contributor.authorGolia, Sarojen_US
dc.contributor.authorMehra, S Ken_US
dc.contributor.authorJani, Manoj Ven_US
dc.date.accessioned2019-11-16T07:27:36Z
dc.date.available2019-11-16T07:27:36Z
dc.date.issued2018-10
dc.description.abstractBackground: Hepatitis B virus infection is a major global health problem and India accounts for 10- 15%of the entire pool of HBV carriers of the world. Prevalence of Hepatitis B in pregnant women worldwide is 2.5 to 1.5%, whereas in India it is 2 to 7%. Hepatitis B virus is a double stranded DNA virus. The study was undertaken to determine the seroprevalence of Hepatitis B among the pregnant women in southern part of Rajasthan at a rural based tertiary care teaching hospital. Methods: This is a prospective study conducted at a tertiary care hospital, Udaipur, Rajasthan, from August 2015 to December 2017.Blood samples were collected from 1011 pregnant women with age ranging from 15- 45 years. Screening of HBsAg was done by RPHA method and positive HBsAg tests were confirmed by ELISA. The data of those , who were found to be positive for HBsAg was statistically analyzed with the chi square tests, and results were considered significant if the p value was <0.05. Results: The overall HBsAg seroprevalence rate was 1.28%, among the total 1011 pregnant women included in this study. HBsAg seroprevalence was highest, (1.64%) in 15-25 years of age group, and 1.71% in the second trimester of pregnancy. The correlations of seroprevalence rate of HBsAg among selected age groups and according to second trimester of pregnancy were not found statistically significant. (p value>0.05) Conclusion: In this study the seroprevalence of Hepatitis B surface antigen was 1.28%. To prevent vertical transmission in the pregnant women, they should be screened for HBsAg at the first antenatal visit for appropriate management.en_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, Ananta Institute of Medical Sciences Research Centre, Rajsamand.en_US
dc.identifier.affiliationsProfessor, Department of Microbiology, Ananta Institute of Medical Sciences Research Centre, Rajsamand.en_US
dc.identifier.affiliationsEx- Professor & Head of The Department, Department of Microbiology, Geetanjali Medical College & Hospital, Udaipur.en_US
dc.identifier.affiliationsAssistant Professor, Department of TB and Chest, Ananta Institute of Medical Sciences Research Centre, Rajsamanden_US
dc.identifier.citationSharma Megha, Golia Saroj, Mehra S K, Jani Manoj V. Seroprevalence & Risk Factors of Hepatitis B Surface Antigen among Pregnant Women Attending a Tertiary Care Hospital of Southern Rajasthan, India. International Archives of BioMedical and Clinical Research. 2018 Oct-Dec; 4(4): 77-79en_US
dc.identifier.issn2454-9894
dc.identifier.issn2454-9886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184520
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber4en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.21276/iabcr.2018.4.4.23en_US
dc.subjectHepatitis B surface antigenen_US
dc.subjectpregnant womenen_US
dc.subjectVertical Transmissionen_US
dc.titleSeroprevalence & Risk Factors of Hepatitis B Surface Antigen among Pregnant Women Attending a Tertiary Care Hospital of Southern Rajasthan, Indiaen_US
dc.typeJournal Articleen_US
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