Antibodies among healthy population of developing countries against enterohaemorrhagic Escherichia coli O157:H7.

dc.contributor.authorVoravuthikunchai, Supayang Piyawanen_US
dc.contributor.authorChaowana, Chitamasen_US
dc.contributor.authorPerepat, Prarinen_US
dc.contributor.authorIida, Tetsuyaen_US
dc.contributor.authorHonda, Takeshien_US
dc.date.accessioned2005-12-08en_US
dc.date.accessioned2009-05-27T03:49:39Z
dc.date.available2005-12-08en_US
dc.date.available2009-05-27T03:49:39Z
dc.date.issued2005-12-08en_US
dc.descriptionJournal of Health, Population, and Nutrition.en_US
dc.description.abstractIn Thailand, no reports are available on Escherichia coli serotype O157:H7, a causative agent of severe bloody diarrhoea, sometimes associated with haemolytic-uraemic syndrome and thrombotic thrombocytopenic purpura. The reason for the non-identification of infection due to E. coli O157 in this country and in other developing countries has not been rigorously discussed. The aim of this study was to determine the humoral response against the infectious organism. The IgM and IgG antibody responses against E. coli O157 lipopolysaccharide were studied using indirect enzyme-linked immunosorbent assay. Three hundred and thirty-two serum samples obtained from healthy blood donors and patients with diseases unrelated to diarrhoea were investigated. With a cut-off value of mean +2 SDs for each age-group, the frequency of the IgM and IgG responses to O157 lipopolysaccharide was 11.74% (39 of 332 samples) and 22.59% (75 of 332 samples) respectively. Furthermore, agglutination test of 173 subjects revealed titres ranging from 10 to 40 in all the samples. The results suggest possible exposure of the Thai population to cross-reacting antigens from other intestinal organisms in addition to infection due to E. coli O157:H7.en_US
dc.description.affiliationDepartment of Microbiology, Faculty of Science, Prince of Songkla University, Hatyai, Songkla 90112, Thailand. supayang.v@psu.ac.then_US
dc.identifier.citationVoravuthikunchai SP, Chaowana C, Perepat P, Iida T, Honda T. Antibodies among healthy population of developing countries against enterohaemorrhagic Escherichia coli O157:H7. Journal of Health, Population, and Nutrition. 2005 Dec; 23(4): 305-10en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/610
dc.language.isoengen_US
dc.source.urihttps://www.icddrb.org/pub/publication.jsp?classificationID=30&typeClassificationID=2en_US
dc.source.urihttps://www.icddrb.org/publication.cfm?classificationID=30&pubID=6611en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgglutination Tests --methodsen_US
dc.subject.meshAntibodies, Bacterial --blooden_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDeveloping Countriesen_US
dc.subject.meshEnzyme-Linked Immunosorbent Assay --methodsen_US
dc.subject.meshEscherichia coli O157 --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulin G --immunologyen_US
dc.subject.meshImmunoglobulin M --immunologyen_US
dc.subject.meshInfanten_US
dc.subject.meshJapanen_US
dc.subject.meshLipopolysaccharides --immunologyen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshReference Valuesen_US
dc.subject.meshThailanden_US
dc.titleAntibodies among healthy population of developing countries against enterohaemorrhagic Escherichia coli O157:H7.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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