Thermal stability of penicillin G acylase : effect of stabilizing agents.
dc.contributor.author | More, V K | en_US |
dc.contributor.author | Shewale, J G | en_US |
dc.contributor.author | Sudhakaran, V K | en_US |
dc.date.accessioned | 1998-02-12 | en_US |
dc.date.accessioned | 2009-05-27T04:15:13Z | |
dc.date.available | 1998-02-12 | en_US |
dc.date.available | 2009-05-27T04:15:13Z | |
dc.date.issued | 1998-02-12 | en_US |
dc.description.abstract | The role of sugars, polyhydroxy compounds, phenylacetic acid and 6-aminopenicillanic acid in stabilization of immobilized penicillin G acylase (IMPGA) was studied. The loss in the activity of IMPGA at 50 degrees C, 2 h, after incorporation of sucrose and mannitol at 0.1 M concentration was 16 and 18% respectively; the loss in the activity of the enzyme under these conditions in the absence of stabilizing agents was 40%. | en_US |
dc.description.affiliation | Research and Development, Hindustan Antibiotics Ltd., Pimpri, Pune 411 018, India. | en_US |
dc.identifier.citation | More VK, Shewale JG, Sudhakaran VK. Thermal stability of penicillin G acylase : effect of stabilizing agents. Hindustan Antibiotics Bulletin. 1998 Feb-Nov; 40(1-4): 1-4 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/2560 | |
dc.language.iso | eng | en_US |
dc.subject.mesh | Carbohydrates --pharmacology | en_US |
dc.subject.mesh | Enzyme Stability | en_US |
dc.subject.mesh | Enzymes, Immobilized --chemistry | en_US |
dc.subject.mesh | Hot Temperature | en_US |
dc.subject.mesh | Penicillin Amidase --chemistry | en_US |
dc.subject.mesh | Polymers --pharmacology | en_US |
dc.title | Thermal stability of penicillin G acylase : effect of stabilizing agents. | en_US |
dc.type | Journal Article | en_US |
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