Usage of prophylactic antibiotics in uncomplicated gynecologic abdominal surgery in Siriraj hospital.

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dc.contributor.authorBoriboonhirunsarn, Dittakarnen_US
dc.contributor.authorLauwahutanont, Piyawaten_US
dc.contributor.authorKaewmanee, Kanyaen_US
dc.contributor.authorHangsubcharoen, Montaen_US
dc.contributor.authorUppagan, Rapepanen_US
dc.contributor.authorMakanantakosol, Supreedaen_US
dc.date.accessioned2009-05-27T20:53:39Z
dc.date.available2009-05-27T20:53:39Z
dc.date.issued2007-06-13en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To determine the rate of prophylactic antibiotics usage in uncomplicated gynecologic abdominal surgery in Siriraj Hospital, before and after guideline implementation. MATERIAL AND METHOD: Two hundred and fifty-eight women who underwent elective gynecologic surgery for a benign condition were enrolled. The patients were divided into two groups, before and after guideline implementation (control and study group). Medical records of these women were reviewed to determine the rate of prophylactic antibiotics usage, rate of postoperative infection, and antibiotics cost. RESULTS: The most common prophylactic antibiotics used were Cefazolin (41.9%), Cefoxitin (36.4%), and Augmentin (9.7%). Rate of single dose of cefazolin usage were not significantly different between the two groups (10.1% and 12.4% respectively, p = 0.482). However, the rate of postoperative oral antibiotic usage was significantly decreased (31.8% and 14.7% respectively, p = 0.001). The reduction of oral antibiotic usage was significant among staff only. The rate of postoperative infection between control and study groups, as well as between single and other antibiotic prophylaxis were similar. Had a single dose of cefazolin been administered to all patients, the antibiotics cost would have been reduced by 102,012 Baht or 91.8%. CONCLUSION: Rate of a single dose of cefazolin usage as antibiotic prophylaxis in gynecologic surgery was similar to before guideline implementation. However, postoperative oral antibiotics usage decreased significantly, especially among the staff.en_US
dc.description.affiliationDepartment of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.en_US
dc.identifier.citationBoriboonhirunsarn D, Lauwahutanont P, Kaewmanee K, Hangsubcharoen M, Uppagan R, Makanantakosol S. Usage of prophylactic antibiotics in uncomplicated gynecologic abdominal surgery in Siriraj hospital. Journal of the Medical Association of Thailand. 2007 Jun; 90(6): 1068-73en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/43826
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdulten_US
dc.subject.meshAmoxicillin-Potassium Clavulanate Combination --therapeutic useen_US
dc.subject.meshAnti-Bacterial Agents --therapeutic useen_US
dc.subject.meshAntibiotic Prophylaxis --economicsen_US
dc.subject.meshBacterial Infections --prevention & controlen_US
dc.subject.meshCefazolin --therapeutic useen_US
dc.subject.meshCefoxitin --therapeutic useen_US
dc.subject.meshDrug Utilization Reviewen_US
dc.subject.meshFemaleen_US
dc.subject.meshGynecologic Surgical Proceduresen_US
dc.subject.meshHospital Costsen_US
dc.subject.meshHumansen_US
dc.subject.meshSurgical Procedures, Electiveen_US
dc.subject.meshSurgical Wound Infection --economicsen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleUsage of prophylactic antibiotics in uncomplicated gynecologic abdominal surgery in Siriraj hospital.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
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