Cefoperazone monotherapy for serious infections in hospitalized patients--an initial Indian experience.

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dc.contributor.authorShah, S Sen_US
dc.contributor.authorDeshpande, A Ken_US
dc.contributor.authorKaundinya, D Ven_US
dc.date.accessioned1995-06-01en_US
dc.date.accessioned2009-05-31T01:20:05Z
dc.date.available1995-06-01en_US
dc.date.available2009-05-31T01:20:05Z
dc.date.issued1995-06-01en_US
dc.description.abstractCefoperazone sodium is a broad spectrum third generation Cephalosporin recently introduced in India. This was used as a monotherapy to treat severe infections in hospitalized patients. These infections were due to various gram positive and gram negative organisms. Of the 22 evaluable patients, 21 (95%) were clinically cured and 1 (5%) improved. 18 pathogens were isolated from 17 patients. Microbiologic eradication was 100%. Symptomatic improvement occurred within 48-72 hours of onset of therapy with complete relief by 4-5 days. Dual mode of excretion makes this drug safe in presence of renal insufficiency. Anti-microbial activity against a wide spectrum of organisms and twice daily dosage schedule qualify Cefoperazone as a single antibiotic of choice in severe infections in critically ill patients.en_US
dc.description.affiliationDept. of Microbiology, Grant Medical College, Bombay.en_US
dc.identifier.citationShah SS, Deshpande AK, Kaundinya DV. Cefoperazone monotherapy for serious infections in hospitalized patients--an initial Indian experience. Journal of the Association of Physicians of India. 1995 Jun; 43(6): 398-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/92084
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshBacteremia --drug therapyen_US
dc.subject.meshCefoperazone --pharmacologyen_US
dc.subject.meshCephalosporins --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGram-Negative Bacterial Infections --drug therapyen_US
dc.subject.meshGram-Positive Bacterial Infections --drug therapyen_US
dc.subject.meshHospitalizationen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshInjections, Intravenousen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTreatment Outcomeen_US
dc.titleCefoperazone monotherapy for serious infections in hospitalized patients--an initial Indian experience.en_US
dc.typeClinical Trialen_US
dc.typeJournal Articleen_US
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