Cytomorphometric analysis of oral squames Tobacco Smokers using oral brush biopsy: An exfoliative cytological study

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dc.contributor.authorShetty, Ren_US
dc.contributor.authorMukherjee, Sen_US
dc.contributor.authorDutta, Nen_US
dc.contributor.authorBhagat, DKen_US
dc.contributor.authorSushma, KNen_US
dc.contributor.authorPandey, V.en_US
dc.date.accessioned2019-12-02T09:52:23Z
dc.date.available2019-12-02T09:52:23Z
dc.date.issued2016
dc.description.abstractBackground: Tobacco is mostly regarded as one of the primary etiologic factor in causing oral cancer. Literature quotes studies have depicted the alteration of nuclear (NA) and cytoplasmic area (CA) induced by tobacco smoking and chewing. Also some authors have stressed on quantifying the role of cytomorphometric analysis in analysing these cellular alterations. Therefore, we evaluated the cytological and cytomorphometric changes in the oral squames using brush biopsy from buccal mucosa of tobacco users. Materials and methods: 200 patients of age group of 40-65 years attending the hospital OPD with history of smoking were included in the study. The patients were broadly divided into two groups; Shetty R, Mukherjee S, Dutta N, Bhagat DK, Sushma K N, Pandey V. Cytomorphometric analysis of oral squames Tobacco Smoker’s using oral brush biopsy: An exfoliative cytological study. IAIM, 2016; 3(5): 14-19. Page 15 smokers (n=150) and Non-smokers (n=50). The cytological samples were taken from clinically normal appearing oral mucosa, stained and analysed using Image analysing software. IndependentSamples T Test and One-Way ANOVA were used to assess the level of significance. Results: significant increase in Mean NA was observed in smokers as compared to non-smokers. Also, Mean CA decreased in smoker’s group as compared to non-smokers. Likewise, N/C ratio was found to be significantly elevated in smokers group. Cytomorphometric parameter changes showed significant alteration with increasing duration of smoking. Conclusion: Cytomorhometric analysis can be used to analyse the alterations occurring in cellular and nuclear level.en_US
dc.identifier.affiliationsSenior Lecturer, Department of Oral pathology, Vananchal Dental College and Hospital, Garhwa, Jharkhand, Indiaen_US
dc.identifier.affiliationsSenior Lecturer, Department of Oral and maxillofacial Sugery, Vananchal Dental College and Hospital, Garhwa, Jharkhand, Indiaen_US
dc.identifier.affiliationsPG Student, Department of Oral Pathology, Vananchal Dental College and Hospital, Garhwa, Jharkhand, Indiaen_US
dc.identifier.affiliationsSenior Lecturer, Department of Oral and maxillofacial Sugery, Vananchal Dental College and Hospital, Garhwa, Jharkhand, Indiaen_US
dc.identifier.affiliationsReader, Department of Periodontology, Vananchal Dental College and Hospital, Garhwa, Jharkhand, India, drvijayendrapandey@yahoo.comen_US
dc.identifier.citationShetty R, Mukherjee S, Dutta N, Bhagat DK, Sushma KN, Pandey V.. Cytomorphometric analysis of oral squames Tobacco Smokers using oral brush biopsy: An exfoliative cytological study. International Archives of Integrated Medicine. 2016 May; 3(5): 14-19en_US
dc.identifier.issn2394-0026
dc.identifier.issn2394-0034
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/186397
dc.languageenen_US
dc.publisherEducational Society for Excellenceen_US
dc.relation.issuenumber5en_US
dc.relation.volume3en_US
dc.subjectCytomorphometryen_US
dc.subjectExfoliativeen_US
dc.subjectSmokingen_US
dc.titleCytomorphometric analysis of oral squames Tobacco Smokers using oral brush biopsy: An exfoliative cytological studyen_US
dc.typeJournal Articleen_US
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