The Surveillance of Drug Resistant Tuberculosis in the Lower North of Thailand between 2005-2007

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Date
2010-04-09
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Thai Journal of Tuberculosis Chest Diseases and Critical Care
Abstract
This retrospective study is done to determine situation and trend of multi-drug resistant tuberculosis (MDR-TB). The whole study retrieved 2,901 clinical specimens (sputum pus blood and urine) from hospitals in control of The Office of Diseases Prevention and Control 9th Phitsanulok, 2006-2008. There were 392 drug susceptibility tests (13.48%) form The national tuberculosis reference laboratory. The result revealed drug resistance for isoniazid (H) 43 (11%), rifampicin (R) 14 (3.58%), streptomycin (S) 28 (7.16%) isoniazid (H) 6 (1.53%). H with R (1.79%), H with S (1.53%), H with E (0.26%), H with S and E (0.77%), S with R and E (0.26%), H with R and E (1.79%), H with R and S (1.54%), resistance for all drugs 4.6%. There were 20 MDR-TB cases (5.12%) and nontuberculous mycobacteria, (NTM) 18 cases (4.6%). MDR-TB is the best index for National TB programme treatment quality and TB planning. This study shows high prevalence and upward trend for MDR-TB. However, this study retrieved some specimens from this area. It is possible that there were more cases of MDR-TB in this area.
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Thai Journal of Tuberculosis Chest Diseases and Critical Care; Vol.30 No.2 April-June 2009; 94-99