Promise(s) of using mesenchymal stem cells in reproductive disorders.

Simple item page
dc.contributor.authorVenkatesan, Vijayalakshmi
dc.contributor.authorMadhira, Soundarya Lakshmi
dc.date.accessioned2015-03-23T08:55:46Z
dc.date.available2015-03-23T08:55:46Z
dc.date.issued2014-11
dc.description.abstractIn recent times, infertility among both man and woman has become a major concern affecting about 20 per cent of the population worldwide and has been attributed in part to several aetiological factors such as changes in lifestyle, which includes sedentary life, dietary habits, sleep anomalies, environmental pollution, etc. Assisted reproductive technologies (ART) have come to the rescue of many such couples, but presence of metabolic disorders such as obesity, diabetes with insulin resistance (IR) and its secondary complications (micro- and macro-vascular complications), become confounders to the outcome of ART. Cell therapies are arising as a new hope in the management of reproductive disorders and currently, the efficacy of mesenchymal stem cells (MSCs) harvested from the adult sources finds wide application in the management of diseases like stroke, neuropathy, nephropathy, myopathy, wounds in diabetes, etc. Given the capacity of MSCs to preferentially home to damaged tissue and modulate the cellular niche/microenvironment to augment tissue repairs and regeneration, the present review outlines the applications of MSCs in the management of infertility/reproductive disorders.en_US
dc.identifier.citationVenkatesan Vijayalakshmi, Madhira Soundarya Lakshmi. Promise(s) of using mesenchymal stem cells in reproductive disorders. Indian Journal of Medical Research. 2014 Nov ; 140 (1_Suppl):s98-s105.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/157120
dc.language.isoenen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345762/en_US
dc.subjectdiabetesen_US
dc.subjectinfertilityen_US
dc.subjectmesenchymal stem cellsen_US
dc.subjectmetabolic syndromeen_US
dc.subjectobesityen_US
dc.subjectWNIN obese mutant ratsen_US
dc.subject.meshAdult
dc.subject.meshAnimals
dc.subject.meshDiabetes Complications
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshInfertility --etiology
dc.subject.meshInfertility --physiopathology
dc.subject.meshInfertility --therapy
dc.subject.meshMale
dc.subject.meshMesenchymal Stem Cell Transplantation --methods
dc.subject.meshMetabolic Syndrome X --complications
dc.subject.meshRats
dc.titlePromise(s) of using mesenchymal stem cells in reproductive disorders.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijmr2014v140n_Suppl1p_s98.pdf
Size:
368.14 KB
Format:
Adobe Portable Document Format
Description:
Review article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Medical Research