Comparison of HIV Antibody Detection by Conventional Method and Dried Tube Specimen : Stability and Validation Study for HIV Serology.
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Date
2011-06
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Abstract
This study was carried out to compare HIV antibody detection by
conventional method and serum dried in test tube and to check the
stability of dried tube specimen (DTS) at ambient temperature.
A total of 50 serum samples were tested for HIV antibodies, which were
sent for testing in the state reference laboratory, by conventional method
according to NACO guidelines. The same serum samples were dried in
test tubes and then after elution with PBS again tested for HIV
antibodies by same method and kits at 0 day and after 30 days.
DTS eluted by PBS showed linear correlation to the serum samples. The
antibodies in DTS were found to be stable at 37o c up to 30 days. This
method is simple, sensitive and specific and can be used in resource
limited settings embarking on scaling up of HIV testing.
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Keywords
HIV, DTS, Conventional method
Citation
Chopra Shashi, Arora Usha. Comparison of HIV Antibody Detection by Conventional Method and Dried Tube Specimen : Stability and Validation Study for HIV Serology. Journal of Communicable Diseases. 2011 Jun; 43(2): 127-129.