Safety and Tolerability of Nonspecific Antidiarrheals in Children with Acute Diarrhea

Simple item page
dc.contributor.authorShanmugham, S. Bhuvaneshwari T.en_US
dc.contributor.authorDange, Suresh V.en_US
dc.contributor.authorTilak, Abhijeet V.en_US
dc.contributor.authorNandagavli, Madhukant H.en_US
dc.date.accessioned2020-09-24T07:09:02Z
dc.date.available2020-09-24T07:09:02Z
dc.date.issued2019-02
dc.description.abstractIntroduction: In clinical practice, nonspecific antidiarrhealsare most commonly used by clinicians along with routinetreatment to hasten the recovery. This study was conductedto to study the safety and tolerability of these nonspecificantidiarrheals in children with acute diarrhea.Material and Methods: This was a prospective, observationalstudy done in clinical settings for a period of 3 years at twopediatric clinics and at a tertiary care hospital. Children weredivided into 5 treatment groups (viz, control, racecadotril,Mebarid, Diarex and loperamide) at the discretion of thepediatrician. One questionnaire was provided to parents torecord the details about the course of diarrhea and parentswere sensitized to report any adverse event.Results: Overall occurrence of adverse events wassignificantly higher in racecadotril group (34.86%) comparedto other groups (C:23.16%, M:21.14%, D:17.95%, L:17.65%).Conclusion: These agents may be safe, effective andinexpensive addition to the routine treatment of acute diarrhea.en_US
dc.identifier.affiliationsAssistant Professor, Department of Pharmacology, Andaman and Nicobar Islands Institute of Medical Sciences (ANIIMS), Port Blairen_US
dc.identifier.affiliationsProfessor, Department of Pharmacology, D.Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil University Pimpri, Pune, Maharashtraen_US
dc.identifier.affiliationsProfessor and HOD, Department of Pharmacology, D.Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil University, Pimpri, Pune, Maharashtraen_US
dc.identifier.affiliationsConsultant Pathologist, Medifriend Path Lab, Chakan, Pune, Maharashtra, Indiaen_US
dc.identifier.citationShanmugham S. Bhuvaneshwari T., Dange Suresh V., Tilak Abhijeet V., Nandagavli Madhukant H.. Safety and Tolerability of Nonspecific Antidiarrheals in Children with Acute Diarrhea. International Journal of Contemporary Medical Research . 2019 Feb; 6(2): b1-b4en_US
dc.identifier.issn2393-915X
dc.identifier.issn2454-7379
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/202204
dc.languageenen_US
dc.publisherInternational Society for Contemporary Medical Researchen_US
dc.relation.issuenumber2en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org//10.21276/ijcmr.2019.6.2.33en_US
dc.subjectAcute Diarrheaen_US
dc.subjectDiarexen_US
dc.subjectLoperamideen_US
dc.subjectMebariden_US
dc.subjectRacecadotrilen_US
dc.subjectNonspecific Antidiarrhealsen_US
dc.subjectSafetyen_US
dc.titleSafety and Tolerability of Nonspecific Antidiarrheals in Children with Acute Diarrheaen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijcmr2019v6n2ppb1.pdf
Size:
245.71 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Contemporary Medical Research