Effect of antimicrobials on cholesterol synthesis and content in liver and small intestines.

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dc.contributor.authorPugalendhi, K Ven_US
dc.contributor.authorSudhakaran, P Ren_US
dc.contributor.authorRamakrishnan, Sen_US
dc.date.accessioned2009-05-28T16:17:37Z
dc.date.available2009-05-28T16:17:37Z
dc.date.issued1992-02-01en_US
dc.description.abstractThe antimicrobials tetracycline, ampicillin and bactrim (cotrimoxazole) decreased HMG CoA reductase activity in liver and small intestines of albino rats. Diminished incorporation of 1, 2, 14C acetate into cholesterol of small intestines in bactrim group was noted. There was a significant fall in cholesterol content of liver, duodenum, jejunum and ileum of the bactrim group and jejunum only in tetracycline group.en_US
dc.description.affiliationDepartment of Biochemistry, Rajah Muthiah Medical College & Hospital, Annamalai University, Annamalainagar, India.en_US
dc.identifier.citationPugalendhi KV, Sudhakaran PR, Ramakrishnan S. Effect of antimicrobials on cholesterol synthesis and content in liver and small intestines. Indian Journal of Experimental Biology. 1992 Feb; 30(2): 152-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/63051
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAmpicillin --pharmacologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCholesterol --biosynthesisen_US
dc.subject.meshHydroxymethylglutaryl CoA Reductases --metabolismen_US
dc.subject.meshIntestine, Small --drug effectsen_US
dc.subject.meshLiver --drug effectsen_US
dc.subject.meshRatsen_US
dc.subject.meshTetracycline --pharmacologyen_US
dc.subject.meshTrimethoprim-Sulfamethoxazole Combination --pharmacologyen_US
dc.titleEffect of antimicrobials on cholesterol synthesis and content in liver and small intestines.en_US
dc.typeJournal Articleen_US
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