Fructose-1, 6-bisphosphatase in human fetal brain and liver during development.
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Date
1982-06
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Abstract
Activity of fructose-1,6-bisphosphatase (EC 3.1.3.11), one of the key gluconeogenic
enzymes, was measured in human fetal brain and liver during development. Fructose-1,6-
bisphosphatase was distributed throughout the different regions of the brain. In contrast to
the partially purified enzyme from the brain, the liver enzyme was dependent on Mg2+ for
maximal activity, EDTA, citrate, oleate and linoleate were stimulatory, whereas 5'-AMP
inhibited the activity of the liver enzyme.
Description
Keywords
Human fetus, brain and liver fructose bisphosphatase, fructose-phosphate interconversion, myo—inositol synthesis
Citation
Biswas Tapas, Majumder Arun Lahiri, Thakurta Gitanjali Guha, Mukherjee K L. Fructose-1, 6-bisphosphatase in human fetal brain and liver during development. Journal of Biosciences. 1982 Jun; 4(2): 167-173.