No reflow phenomenon in CAD patients after percutaneous coronary intervention: A prospective hospital based observational study

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Date
2023-04
Journal Title
Journal ISSN
Volume Title
Publisher
Cardiological Society of India
Abstract
The present study assessed incidence, risk factors, in-hospital and short-term outcomes associated with no-reflow in patients undergoing percutaneous coronary intervention (PCI) in STEMI, NSTEMI, unstable angina and stable angina. Out of 449 patients, 42 (9.3%) developed no-reflow. Hypertension, dyslipidemia, obesity and smoking were significant risk factors. There was significant association of no-reflow with left main disease, multiple stents, target lesion length_x0001_ 20 mm and higher thrombus grade. Interestingly, 93 patients (23.4%) of normal flow had myocardial perfusion grade (MPG) of 0/1 with mortality in 9 (10%) patients. No-reflow is associated with poor in-hospital and short-term outcomes with higher incidence of death, cardiogenic shock, heart failure and MACE. Knowledge of risk factors of no-reflow portends a more meticulous approach to improve final outcomes. MPG could be better predictor of outcomes in these patients.
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Keywords
No-reflow phenomenon, Percutaneous coronary intervention, Thrombolysis in myocardial infarction, (TIMI)
Citation
Rao Shivani, Bhardwaj Rajeev, Negi P.C., Nath Ranjit Kumar. No reflow phenomenon in CAD patients after percutaneous coronary intervention: A prospective hospital based observational study. Indian Heart Journal. 2023 Apr; 75(2): 156-159