Radiological determination of gastric motility in experimental model treated with Rosmarinus officinalis Linn. (Lamiaceae) extracts

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dc.contributor.authorCarnevali, Taiane Ritaen_US
dc.contributor.authorWaller, Stefanie Bressanen_US
dc.contributor.authorFerrasso, Marina de Mattosen_US
dc.contributor.authorJúnior, Anacleto de Souza Rosaen_US
dc.contributor.authorCarapeto, Luiz Paivaen_US
dc.contributor.authorFreitag, Rogério Antônioen_US
dc.contributor.authorSchuch, Luiz Filipe Daméen_US
dc.contributor.authorCleff, Marlete Brumen_US
dc.date.accessioned2020-01-02T06:38:43Z
dc.date.available2020-01-02T06:38:43Z
dc.date.issued2019-09
dc.description.abstractAmong the biological properties of Rosmarinus officinalis Linn. (rosemary), the infusions and ethanolic extracts are popularly used to treat gastrointestinal disorders. However, the effects of these extracts on the gastric motility are unknown. Here, we evaluated influence of the rosemary extracts on gastric motility and its chemical composition. Forty-eight female Wistar rats with food restriction for 12 h were made into eight experimental groups (n=6, each) and given oral treatments (1 mL) of ethanolic and aqueous extracts at the doses of 125, 250 and 500 mg/kg, and distilled water (control) and metoclopramide (2 mg/kg, intramuscular). After one hour, five metal spheres (1 mm) were administered with barium contrast. A series of radiographs were taken every hour for six hours. Significant differences were shown in the gastric emptying of the metal spheres within three hours among the extracts and the control groups. By high-performance liquid chromatography (HPLC), both extracts presented kaempferol, carnosic acid and rosmarinic acid as major compounds, which would influence in the higher time for emptying. This study showed that the rosemary extracts increased the gastric emptying time in healthy rats, suppressing the gastric motility, and may be useful in treating digestive disorders, like diarrhea.en_US
dc.identifier.affiliationsDepartamento de Clínicas Veterinária, Faculdade de Veterinária, Universidade Federal de Pelotas, Pelotas/RS, Brasilen_US
dc.identifier.affiliationsDepartamento de Química Orgânica, Instituto de Química e Geociências, Universidade Federal de Pelotas, Pelotas/RS, Brasilen_US
dc.identifier.citationCarnevali Taiane Rita, Waller Stefanie Bressan, Ferrasso Marina de Mattos, Júnior Anacleto de Souza Rosa, Carapeto Luiz Paiva, Freitag Rogério Antônio, Schuch Luiz Filipe Damé, Cleff Marlete Brum. Varietal variation in physiological and biochemical attributes of sugarcane varieties under different soil moisture regimes. Indian Journal of Experimental Biology. 2019 Sep; 57(9): 721-732en_US
dc.identifier.issn0975-1009
dc.identifier.issn0019-5189
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/191514
dc.languageenen_US
dc.publisherNISCAIR-CSIR, Indiaen_US
dc.relation.issuenumber9en_US
dc.relation.volume57en_US
dc.source.urihttps://nopr.niscair.res.in/handle/123456789/50448en_US
dc.titleRadiological determination of gastric motility in experimental model treated with Rosmarinus officinalis Linn. (Lamiaceae) extractsen_US
dc.typeJournal Articleen_US
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