Assessment Of Serum Lipid Profile In Hypertensive Patients: A Case-control Study
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Date
2020-01
Journal Title
Journal ISSN
Volume Title
Publisher
Sumathi Publications
Abstract
Background: Hypertension and dyslipidemia are strongly associated with each other, and they are the most common risk factors for the development of the cardiovascular disease. Aim:Compare the serum lipid profile values among hypertensive patients and non-hypertensive individuals. Method:30 patients with Hypertension and 30 age-matched non-hypertensive controls were included in the study. From the serum, total cholesterol levels were estimated by enzymatic (CHOD-PAP) colorimetric method, triglyceride by enzymatic (GPO-PAP) method, HDL-cholesterol and LDL-cholesterol were estimated using precipitant and Friedewald formula, by using commercially available reagent kits. Lipid profiles were compared with controls. Results:The mean values of total cholesterol were significantly more in Hypertensives-202.93 ± 28.44 and normotensives-178.76 ± 37.21, P<0.006. The mean values of triglycer-ides were significantly more in Hypertensives-139.8 ± 18.72 and normotensives-125.8± 12.34, P<0.001. The mean values of LDL-Cholesterol were significantly more in Hypertensives-141.63 ± 11.59 and normotensives-127.83 ± 14.65, P<0.0001. Conclusions:As Dyslipidemia is associated with Hypertension, serum lipid profile may be useful in the identification of patients at risk of Hypertension. Hypertensive patients need the measurement of blood pres-sure and lipid profile at regular intervals to prevent Cardiovascular diseases.
Description
Keywords
Cholesterol, Cardiovascular Diseases, Hypertension, Triglycerides, Dyslipidemia
Citation
V Sushma Reddy, TV Hari Prasad, B V Surendra . Assessment Of Serum Lipid Profile In Hypertensive Patients: A Case-control Study. International Journal of Clinical and Biomedical Research. 2020 Jan; 6(1): 21-24