A review of the SARS-CoV-2 viral genome mutation and its effects
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Date
2023-03
Journal Title
Journal ISSN
Volume Title
Publisher
Association of Biomedical Scientists
Abstract
The pandemic-starting SARS-CoV-2 novel coronavirus was found in Wuhan, China. WHO declared this pandemic, which began in late 2019, in March 2020. Experts say this was the first SARS-CoV-2 outbreak. It was the first of many. This virus constantly mutates in response to its replication environment, causing waves, the deadliest of which was the delta variant-caused second wave, which killed millions worldwide. This review examines viral genome alterations and their global effects. We used references from previous research articles on this or similar issues to make our review more data-driven. We found that the virus’ mutation has caused major health problems in humans, including deaths. The viruses changed genome, proteins, local food, sanitation, immunity, and milieu may be involved. We also found that while some of the impacted variations are milder and less contagious, some have had record-breaking peaks and significant death rates in a short time. This analysis examines COVID-19’s impact on diabetes, cardiovascular disease, asthma, aging, and community hygiene. SARS-CoV-2 increases stress and blood glucose in diabetics. Clinical investigations have linked COVID-19 to cardiovascular disease, although the mechanism is uncertain. Asthmatics are more vulnerable to respiratory infections. Its effects change as one age. Cleanliness campaigns are needed to put an end to the epidemic.
Description
Keywords
SARSCoV2, COVID19, Mutation, Diabetes, Cardiovascular Diseases, Asthma
Citation
Bhoi Bibekananda, Bhardwaj Himanshu, Kumar Maneesh. A review of the SARS-CoV-2 viral genome mutation and its effects. Southeast Asian Journal of Case Report and Review. 2023 Mar; 10(1): 1-4