Brain tumor and Gliadel wafer treatment.

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dc.contributor.authorPanigrahi, M
dc.contributor.authorDas, P K
dc.contributor.authorParikh, P M
dc.date.accessioned2013-01-16T09:21:17Z
dc.date.available2013-01-16T09:21:17Z
dc.date.issued2011-01
dc.description.abstractGlioblastoma is a rapidly progressive and extremely fatal form of brain tumor with poor prognosis. It is the most common type of primary brain tumor. Even with the most aggressive conventional treatment that comprises surgery followed by radiotherapy and chemotherapy, most patients die within a year of diagnosis. Developments in molecular and cell biology have led to better understanding of tumor development, leading to novel treatment strategies including biological therapy and immunotherapy to combat the deadly disease. Targeted drug delivery strategies to circumvent the blood-brain barrier have shown efficiency in clinical trials. Gliadel wafer is a new approach to the treatment of glioblastoma, which involves controlled release delivery of carmustine from biodegradable polymer wafers. It has shown promising results and provides a silver lining for glioblastoma patients.en_US
dc.identifier.citationPanigrahi M, Das P K, Parikh P M. Brain tumor and Gliadel wafer treatment. Indian Journal of Cancer. 2011 Jan-Mar; 48(1): 11-17.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/144405
dc.language.isoenen_US
dc.source.urihttps://www.indianjcancer.com/article.asp?issn=0019-509X;year=2011;volume=48;issue=1;spage=11;epage=17;aulast=Panigrahien_US
dc.subjectBiological therapyen_US
dc.subject1,3-bis (2-chloroethyl)-1-nitrosourea or carmustineen_US
dc.subjectbrain tumoren_US
dc.subjectchemotherapyen_US
dc.subjectGliadel waferen_US
dc.subjectglioblastomaen_US
dc.subjectgliomasen_US
dc.subjectpolifeprosan 20en_US
dc.subject.meshAntineoplastic Agents, Alkylating --therapeutic use
dc.subject.meshBrain Neoplasms --drug therapy
dc.subject.meshCarmustine --therapeutic use
dc.subject.meshDelayed-Action Preparations
dc.subject.meshHumans
dc.titleBrain tumor and Gliadel wafer treatment.en_US
dc.typeArticleen_US
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