Para-aortic lymph node tracing and dissection in advanced gastric cancer: Effectiveness of carbon nanoparticles injection through the no. 12b lymph node

Simple item page
dc.contributor.authorMu, Guangchuanen_US
dc.contributor.authorHuang, Yuanen_US
dc.contributor.authorWei, Chengzhien_US
dc.contributor.authorChen, Zhibaien_US
dc.contributor.authorWu, Xianghuaen_US
dc.contributor.authorQin, Xinganen_US
dc.contributor.authorZeng, Yanjunen_US
dc.date.accessioned2020-11-18T10:08:17Z
dc.date.available2020-11-18T10:08:17Z
dc.date.issued2020-05
dc.description.abstractBackground and Objectives: The relative effectiveness of tracers in guiding para-aortic lymph node dissection (PAND) in advanced gastric cancer is undefined. In this single-center, prospective study, we aimed to discuss the effectiveness of such tracers. Materials and Methods: Between January 2015 and January 2016, 90 consecutive patients with stage T4a gastric cancer were evenly assigned to receive 0.2 mL of carbon nanoparticles (a), methylene blue (b), or no tracer (c) injection through no. 12b lymph nodes before PAND. Results: There was no difference in the baseline characteristics between the three groups. Group A vs. B or C had a higher number of dissected lymph nodes (34.1 ± 9.8, 25.5 ± 5.5, and 22.6 ± 3.7; P < 0.001; B vs. C: P =0.321) and no. 16a2/b1 para-aortic lymph nodes (PANs; 11.8 ± 4.8, 7.0 ± 1.2, and 5.5 ± 1.2; P < 0.001; B vs. C: P =0.178) and similar rates of lymph node metastasis (20.9 ± 17.5%, 19.1 ± 15.1%, and 23.6 ± 19.7%; P = 0.511), positive dissected PAN (23.3% [7/30], 16.7% [5/30], and 16.7% [5/30]), surgery duration (252.9 + 35.4, 244.4 ± 29.0, and 250.3 + 29.9 min; P = 0.421), and blood loss (266.7 ± 115.5, 270.0 ± 82.6, and 260.0 ± 116.3 mL, P = 0.933). There was no common bile duct damage by tracer injection, and one case of duodenal stump fistula, one abdominal infection, and two anastomotic leakages in Groups A–C, respectively, were treated successfully. Conclusions: In advanced gastric cancer treatment, carbon nanoparticle injection into no. 12b nodes appears to better trace no. 16a2/b1 PANen_US
dc.identifier.affiliationsDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Chinaen_US
dc.identifier.affiliationsDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Chinaen_US
dc.identifier.affiliationsDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Chinaen_US
dc.identifier.affiliationsDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Chinaen_US
dc.identifier.affiliationsDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Chinaen_US
dc.identifier.affiliationsDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Chinaen_US
dc.identifier.affiliationsBiomedical Engineering Center, Beijing University of Technology, Beijing, Chinaen_US
dc.identifier.citationMu Guangchuan, Huang Yuan, Wei Chengzhi, Chen Zhibai, Wu Xianghua, Qin Xingan, Zeng Yanjun. Para-aortic lymph node tracing and dissection in advanced gastric cancer: Effectiveness of carbon nanoparticles injection through the no. 12b lymph node. Journal of Cancer Research and Therapeutics. 2020 May; 16(2): 238-242en_US
dc.identifier.issn0973-1482
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/213806
dc.languageenen_US
dc.publisherWolters Kluwer India Pvt. Ltd.en_US
dc.relation.issuenumber2en_US
dc.relation.volume16en_US
dc.source.urihttps://dx.doi.org//10.4103/jcrt.JCRT_506_19en_US
dc.subjectAdvanced gastric canceren_US
dc.subjectcarbon nanoparticlesen_US
dc.subjectpara‑aortic lymph nodesen_US
dc.subjecttracer agentsen_US
dc.titlePara-aortic lymph node tracing and dissection in advanced gastric cancer: Effectiveness of carbon nanoparticles injection through the no. 12b lymph nodeen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijcrt2020v16n2p238.pdf
Size:
939.06 KB
Format:
Adobe Portable Document Format
Download
Collections
Journal of Cancer Research and Therapeutics