Electrocardiographic and echocardiographic changes in perinatal asphyxia.

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dc.contributor.authorRajakumar, P Sen_US
dc.contributor.authorVishnu Bhat, Ben_US
dc.contributor.authorSridhar, M Gen_US
dc.contributor.authorBalachander, Jen_US
dc.contributor.authorKonar, B Cen_US
dc.contributor.authorNarayanan, Pen_US
dc.contributor.authorChetan, Gen_US
dc.date.accessioned2009-03-15en_US
dc.date.accessioned2009-05-30T15:35:56Z
dc.date.available2009-03-15en_US
dc.date.available2009-05-30T15:35:56Z
dc.date.issued2009-03-15en_US
dc.description.abstractOBJECTIVE: To study the usefulness of cardiac enzymes in evaluating myocardial damage in perinatal asphyxia. METHODS: Thirty term babies with perinatal asphyxia and without any congenital malformations were selected as cases. They were compared with thirty healthy term babies without asphyxia. Myocardial dysfunction was evaluated using clinical, electrocardiography, echocardiography and cardiac enzymes i.e, troponin-T and CK-MB levels. RESULTS: Among the 30 cases 23 had evidence of myocardial involvement while one baby in the control group had ECG evidence compatible with cardiac involvement. Cardiac enzymes were significantly increased in babies with perinatal asphyxia. The mean level of C-troponin-T among cases and controls were 0.22+/-0.28 and 0.003+/-0.018 while CK-MB levels were 121+/-77.4 IU/L and 28.8 +/- 20.2 IU/L respectively. C-troponin-T had higher sensitivity and specificity compared to CK-MB levels. Moreover, C troponin-T levels correlated well with severity and outcome in babies with perinatal asphyxia. CONCLUSION: C-Tropopnin assay is useful in evaluating the severity of myocardial damage and outcome in perinatal asphyxia.en_US
dc.description.affiliationDepartment of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.en_US
dc.identifier.citationRajakumar PS, Vishnu Bhat B, Sridhar MG, Balachander J, Konar BC, Narayanan P, Chetan G. Electrocardiographic and echocardiographic changes in perinatal asphyxia. Indian Journal of Pediatrics. 2009 Mar; 76(3): 261-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/83771
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAsphyxia Neonatorum --complications
dc.subject.meshCardiomyopathies --blood
dc.subject.meshCardiomyopathies --diagnosis
dc.subject.meshCardiomyopathies --etiology
dc.subject.meshCase-Control Studies
dc.subject.meshCreatine Kinase, MB Form --blood
dc.subject.meshEchocardiography
dc.subject.meshElectrocardiography
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshIncidence
dc.subject.meshInfant, Newborn
dc.subject.meshLength of Stay
dc.subject.meshMyocardium --enzymology
dc.subject.meshProspective Studies
dc.subject.meshSensitivity and Specificity
dc.subject.meshTroponin T --blood
dc.titleElectrocardiographic and echocardiographic changes in perinatal asphyxia.en_US
dc.typeJournal Articleen_US
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