Involvement of dietary glucose in adrenal steroidal regulation of spermatogenic and steroidogenic activities in prepubertal rat testis.

Simple item page
dc.contributor.authorSaxena, Nen_US
dc.contributor.authorPaul, P Ken_US
dc.date.accessioned2009-05-28T15:22:08Z
dc.date.available2009-05-28T15:22:08Z
dc.date.issued1991-07-01en_US
dc.description.abstractEffects of dietary and supplemented dextrose energy on the role of corticosterone (Comp. B) or dehydroepiandrosterone (DHA) in spermatogenic and steroidogenic activity in the bilaterally adrenalectomised prepubertal rat testis were studied. Adrenalectomy reduced the body and testis weight, numbers of the stage VII cell types [spermatogonia A (A), preleptotene (PL) and pachytene (P) spermatocytes and step 7 spermatid (7)], testicular delta 5-3 beta-hydroxysteroid dehydrogenase (delta 5-3 beta-OH-SDH) activity and serum testosterone. Adrenalectomy also caused reduction of energy intake due to loss of appetite which was stimulated by hormone replacement therapy. Treatment of adrenalectomised rats with DNA or corticosterone enhanced the spermatocyte population and the enzyme activity, especially after 30 days of age. Dextrose supplementation with hormone treatment however, did not produce significant additive effect on stage VII cell counts, but delta 5-3 beta-OH-SDH activity showed additive effect in this age group. Results suggest that adrenal steroids regulate testicular steroidogenesis and spermatogenesis during the prepubertal ages by modifying the supply of dietary glucose.en_US
dc.description.affiliationDepartment of Zoology, University of Delhi, India.en_US
dc.identifier.citationSaxena N, Paul PK. Involvement of dietary glucose in adrenal steroidal regulation of spermatogenic and steroidogenic activities in prepubertal rat testis. Indian Journal of Experimental Biology. 1991 Jul; 29(7): 605-10en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/61893
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAdrenalectomyen_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAppetite --physiologyen_US
dc.subject.meshCorticosterone --pharmacologyen_US
dc.subject.meshDehydroepiandrosterone --pharmacologyen_US
dc.subject.meshDietary Carbohydrates --pharmacologyen_US
dc.subject.meshGlucose --pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshOrgan Size --drug effectsen_US
dc.subject.meshRatsen_US
dc.subject.meshSexual Maturation --drug effectsen_US
dc.subject.meshSpermatogenesis --drug effectsen_US
dc.subject.meshTestis --anatomy & histologyen_US
dc.subject.meshTestosterone --biosynthesisen_US
dc.titleInvolvement of dietary glucose in adrenal steroidal regulation of spermatogenic and steroidogenic activities in prepubertal rat testis.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Experimental Biology