Modulation of antioxidant potential in liver of mice by kernel oil of cashew nut (Anacardium occidentale) and its lack of tumour promoting ability in DMBA induced skin papillomagenesis.

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dc.contributor.authorSingh, Bimalaen_US
dc.contributor.authorKale, R Ken_US
dc.contributor.authorRao, A Ren_US
dc.date.accessioned2009-05-28T15:16:17Z
dc.date.available2009-05-28T15:16:17Z
dc.date.issued2004-04-20en_US
dc.description.abstractCashew nut shell oil has been reported to possess tumour promoting property. Therefore an attempt has been made to study the modulatory effect of cashew nut (Anlacardium occidentale) kernel oil on antioxidant potential in liver of Swiss albino mice and also to see whether it has tumour promoting ability like the shell oil. The animals were treated orally with two doses (50 and 100 microl/animal/day) of kernel oil of cashew nut for 10 days. The kernel oil was found to enhance the specific activities of SOD, catalase, GST, methylglyoxalase I and levels of GSH. These results suggested that cashew nut kernel oil had an ability to increase the antioxidant status of animals. The decreased level of lipid peroxidation supported this possibility. The tumour promoting property of the kernel oil was also examined and found that cashew nut kernel oil did not exhibit any solitary carcinogenic activity.en_US
dc.description.affiliationRadiation and Cancer Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India.en_US
dc.identifier.citationSingh B, Kale RK, Rao AR. Modulation of antioxidant potential in liver of mice by kernel oil of cashew nut (Anacardium occidentale) and its lack of tumour promoting ability in DMBA induced skin papillomagenesis. Indian Journal of Experimental Biology. 2004 Apr; 42(4): 373-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/61773
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.mesh9,10-Dimethyl-1,2-benzanthracene --toxicityen_US
dc.subject.meshAnacardium --chemistryen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntioxidants --metabolismen_US
dc.subject.meshCarcinogens --toxicityen_US
dc.subject.meshCatalase --metabolismen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlutathione --metabolismen_US
dc.subject.meshGlutathione Transferase --metabolismen_US
dc.subject.meshLactoylglutathione Lyase --metabolismen_US
dc.subject.meshLiver --drug effectsen_US
dc.subject.meshMiceen_US
dc.subject.meshMicrosomes, Liver --drug effectsen_US
dc.subject.meshNuts --chemistryen_US
dc.subject.meshPapilloma --chemically induceden_US
dc.subject.meshPlant Oils --pharmacologyen_US
dc.subject.meshSkin Neoplasms --chemically induceden_US
dc.subject.meshSuperoxide Dismutase --metabolismen_US
dc.titleModulation of antioxidant potential in liver of mice by kernel oil of cashew nut (Anacardium occidentale) and its lack of tumour promoting ability in DMBA induced skin papillomagenesis.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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