Bone marrow trephine biopsy as an adjunct to bone marrow aspiration.

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dc.contributor.authorNanda, Annuen_US
dc.contributor.authorBasu, Sabitaen_US
dc.contributor.authorMarwaha, Neelamen_US
dc.date.accessioned2002-07-20en_US
dc.date.accessioned2009-05-30T17:44:54Z
dc.date.available2002-07-20en_US
dc.date.available2009-05-30T17:44:54Z
dc.date.issued2002-07-20en_US
dc.description.abstractOBJECTIVE: To determine the relative efficacy of bone marrow aspiration as compared to that of trephine biopsy. METHODS: Bone marrow aspiration and bilateral trephine biopsies were performed in 420 consecutive cases. The diagnosis and findings made on bone marrow aspiration were compared with that made on trephine biopsy in each case. RESULTS: Aspiration alone was sufficient in making a diagnosis in 372 (88.6%) cases as it correlated well with the diagnosis made on trephine sections. In the remaining 48 (11.4%) cases trephine biopsy was necessary for making a diagnosis due to incomplete information provided by aspiration or its inability to give a correct diagnosis. These cases were mostly hypoplastic/aplastic marrow, myelofibrosis and marrow involvement by metastatic tumour and lymphomatous infiltration. Often a bilateral marrow biopsy picked up the diagnostic lesion. CONCLUSION: The decision to perform a marrow aspiration alone or in combination with marrow biopsy depends on the diagnosis being considered. In nutritional anaemias, most hematologic malignancies and immune thrombocytopenias, marrow aspiration alone is sufficient, but for detection of disorders with focal marrow involvement bilateral marrow biopsies are a must.en_US
dc.description.affiliationDepartment of Haematology and Transfusion Medicine, Government Medical College, Chandigarh.en_US
dc.identifier.citationNanda A, Basu S, Marwaha N. Bone marrow trephine biopsy as an adjunct to bone marrow aspiration. Journal of the Association of Physicians of India. 2002 Jul; 50(): 893-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/85182
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshBiopsy, Needleen_US
dc.subject.meshBone Marrow --pathologyen_US
dc.subject.meshBone Marrow Diseases --diagnosisen_US
dc.subject.meshHumansen_US
dc.titleBone marrow trephine biopsy as an adjunct to bone marrow aspiration.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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