The Relationship between Loneliness and Suicidal Ideation in Private Medical and Dental Students in Jeddah, Saudi Arabia
Loading...
Date
2018-01
Journal Title
Journal ISSN
Volume Title
Publisher
VXL Publishers
Abstract
Back ground: Inflammatory periodontal disease has been associated with an increased risk of cardiovascularevents. Emerging evidence shows an association of periodontal disease with systemic inflammation andendothelial dysfunction, while the underlying mechanism remains unclear. Circulating cell adhesion moleculesE-selectin has been suggested as a potential candidate marker of endothelial dysfunction, which contributes tothe pathogenesis of cardiovascular diseases. Aim: To determine the serum sE-selectin level in generalisedsevere chronic periodontitis and periodontally healthy subjects. Materials and methods: Eighty subjects in theage group of 35-55 years were included in the study. Forty subjects with generalised severe chronic periodontitisas study group and 40 healthy subjects without periodontal disease as control group were selected. The bloodsamples were collected and the serum was analysed for sE-selectin level by ELISA. Results: sE-selectinexpression was found in serum of both the groups. Mean serum sE-selectin levels were 37.05ng/mL in the studygroup and 30.78ng/mL in control group. Statistically significant increase was not found in serum sE-selectinlevels between the groups. Conclusion: sE-selectin is expressed in serum of both the study and control groupswith a wide range of distribution. No significant association was observed between sE-selectin level andperiodontal inflammation. Therefore, circulating sE-selectin may not be used as a reliable biomarker ofendothelial function measure in periodontal disease.
Description
Keywords
loneliness, suicidal ideation, medical students, dental students, Saudi Arabia
Citation
Aboalshamat Khalid, Salman Wejdan, Almehman Razan, Maghrabi Amal, Alamoudi Khadija, Najjar Amani, Alshehri Aeshah. The Relationship between Loneliness and Suicidal Ideation in Private Medical and Dental Students in Jeddah, Saudi Arabia. Journal of International Medicine and Dentistry. 2018 Jan; 5(1): 11-19