Effect of newly isolated Lactobacillus ingluviei ADK10, from chicken intestinal tract on acetaminophen induced oxidative stress in Wistar rats.

Simple item page
dc.contributor.authorMandal, Arpita
dc.contributor.authorPaul, Tanmay
dc.contributor.authorRoy, Suchismita
dc.contributor.authorMandal, Shreya
dc.contributor.authorPradhan, Shrabani
dc.contributor.authorMondal, Keshab Ch
dc.contributor.authorNandi, Dilip Kumar
dc.date.accessioned2013-07-30T07:05:50Z
dc.date.available2013-07-30T07:05:50Z
dc.date.issued2013-02
dc.description.abstractThe total antioxidative activity of L. ingluviei ADK10 isolated from chicken intestine intact cells and cell free culture supernatant (CFCS) was 54- 67.95%. The ability to scavenge a,a-Diphenyl-b-Picrylhydrazyl free radical ranged from 71 and 64% in intact cells and CFCS respectively. Total reducing activity of bacteria was equivalent to 290 µM/L of cysteine. Reducing glutathione activity was equivalent to 93.95µg/mL. Oral administration of the strain at a dose of 109 cfu/kg body weight to acetaminophen induced oxidative stress in rats increased catalase, glutathione and superoxide dismutase activity in the blood, liver and kidney and lowered malondialdehyde level. The results indicate that L. ingluviei ADK10 has potential free radical scavenging activity for the treatment of oxidative stress related disease.en_US
dc.identifier.citationMandal Arpita, Paul Tanmay, Roy Suchismita, Mandal Shreya, Pradhan Shrabani, Mondal Keshab Ch, Nandi Dilip Kumar. Effect of newly isolated Lactobacillus ingluviei ADK10, from chicken intestinal tract on acetaminophen induced oxidative stress in Wistar rats. Indian Journal of Experimental Biology. 2013 Feb; 51(2): 174-180.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/147581
dc.language.isoenen_US
dc.source.urihttps://nopr.niscair.res.in/handle/123456789/15933en_US
dc.subjectAcetaminophenen_US
dc.subjectFree radical scavenging activityen_US
dc.subjectLactobacillus ingluviei ADK10en_US
dc.subjectOxidative stressen_US
dc.subject.meshAcetaminophen
dc.subject.meshAnimals
dc.subject.meshAntioxidants --metabolism
dc.subject.meshCatalase --blood
dc.subject.meshChickens --microbiology
dc.subject.meshGlutathione --blood
dc.subject.meshIntestines --microbiology
dc.subject.meshKidney --enzymology
dc.subject.meshLactobacillus --classification
dc.subject.meshLactobacillus --isolation & purification
dc.subject.meshLactobacillus --metabolism
dc.subject.meshLiver --enzymology
dc.subject.meshLiver --pathology
dc.subject.meshMale
dc.subject.meshMalondialdehyde --blood
dc.subject.meshMolecular Sequence Data
dc.subject.meshOxidation-Reduction
dc.subject.meshOxidative Stress
dc.subject.meshPhylogeny
dc.subject.meshRats
dc.subject.meshRats, Wistar
dc.subject.meshSuperoxide Dismutase --blood
dc.titleEffect of newly isolated Lactobacillus ingluviei ADK10, from chicken intestinal tract on acetaminophen induced oxidative stress in Wistar rats.en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijeb2013v51n2p174.pdf
Size:
227.66 KB
Format:
Adobe Portable Document Format
Description:
Journal article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Indian Journal of Experimental Biology