Primary biliary cirrhosis: an Indian experience.

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dc.contributor.authorPuri, A Sen_US
dc.contributor.authorKumar, Nen_US
dc.contributor.authorGondal, Ren_US
dc.contributor.authorLamba, G Sen_US
dc.contributor.authorJain, Men_US
dc.date.accessioned2001-01-24en_US
dc.date.accessioned2009-05-29T02:34:35Z
dc.date.available2001-01-24en_US
dc.date.available2009-05-29T02:34:35Z
dc.date.issued2001-01-24en_US
dc.description.abstractPrimary biliary cirrhosis (PBC) is believed to be rare in India. We analyzed our data pertaining to patients with PBC seen in a tertiary referral center over a 5-year period. The diagnosis of PBC was based on liver biochemistry, histology and antimitochondrial antibodies, in the absence of biliary obstruction. Five patients, all women, were diagnosed to have PBC. Pruritus, jaundice and fatigue were the most common initial symptoms. Hepatomegaly was seen in 4 of 5 patients. Associated autoimmune diseases were present in 2 patients. All patients presented with mild hyperbilirubinemia (< or = 6 mg/dL) with disproportionately raised serum alkaline phosphatase level. AMA was positive in 4 patients. Liver biopsy showed stage III-IV disease in 3 of 4 patients. The clinical presentation and course of PBC in India are similar to the experience in the West.en_US
dc.description.affiliationDepartment of Gastroenterology, G B Pant Hospital, New Delhi.en_US
dc.identifier.citationPuri AS, Kumar N, Gondal R, Lamba GS, Jain M. Primary biliary cirrhosis: an Indian experience. Indian Journal of Gastroenterology. 2001 Jan-Feb; 20(1): 28-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/64309
dc.language.isoengen_US
dc.source.urihttps://www.indianjgastro.comen_US
dc.subject.meshAdulten_US
dc.subject.meshBiopsy, Needleen_US
dc.subject.meshCholestyramine --therapeutic useen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshLiver Cirrhosis, Biliary --diagnosisen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRifampin --therapeutic useen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.titlePrimary biliary cirrhosis: an Indian experience.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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