A study of changes in homocysteine levels during normal pregnancy and pre-eclampsia.

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dc.contributor.authorSingh, Urmilaen_US
dc.contributor.authorGupta, H Pen_US
dc.contributor.authorSingh, R Ken_US
dc.contributor.authorShukla, Manjuen_US
dc.contributor.authorSingh, Ranjanaen_US
dc.contributor.authorMehrotra, Seema Sinha Neeen_US
dc.contributor.authorPrasad, Shwetaen_US
dc.date.accessioned2008-08-04en_US
dc.date.accessioned2009-05-31T13:51:51Z
dc.date.available2008-08-04en_US
dc.date.available2009-05-31T13:51:51Z
dc.date.issued2008-08-04en_US
dc.description.abstractTo find out changes in homocysteine levels that occur during normal pregnancy and pregnancy with pre-eclamptic toxaemia and also to find out correlation between homocysteine concentration and preeclamptic toxaemia a study was carried out among 90 women of which 30 were control which included normotensive non-pregnant women and the study group I comprised 30 pregnant normotensive women and the study group II comprised 30 pregnant women with pre-eclamptic toxaemia. Serum homocysteine was measured in all subjects using fluorescence polarisation immuno-assay. Control group had highest mean homocysteine levels while the study group I had least mean homocysteine levels (p < 0.001). Levels were significantly higher in subjects with BP > 146/100 mm Hg as compared to subjects with BP >140/90 and <146/100 mm Hg (p=0.017). There was significant difference between study group I and II at same gestational age. Hyperhomocysteinaemia was observed in pre-eclamptic females, also it was found that homocysteine levels were directly correlated with severity of pre-eclampsia.en_US
dc.description.affiliationDepartment of Obstetrics and Gynaecology, King George's Medical University, Lucknow.en_US
dc.identifier.citationSingh U, Gupta HP, Singh RK, Shukla M, Singh R, Mehrotra SS, Prasad S. A study of changes in homocysteine levels during normal pregnancy and pre-eclampsia. Journal of the Indian Medical Association. 2008 Aug; 106(8): 503-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/102217
dc.language.isoengen_US
dc.source.urihttps://www.jimaonline.org.in/en_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluorescence Polarizationen_US
dc.subject.meshHomocysteine --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshHyperhomocysteinemia --blooden_US
dc.subject.meshMaternal Welfareen_US
dc.subject.meshPerinatal Careen_US
dc.subject.meshPre-Eclampsia --blooden_US
dc.subject.meshPregnancyen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshYoung Adulten_US
dc.titleA study of changes in homocysteine levels during normal pregnancy and pre-eclampsia.en_US
dc.typeJournal Articleen_US
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