Toxic and sub-lethal effects of oleandrin on biochemical parameters of fresh water air breathing murrel, Channa punctatus (Bloch.).

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dc.contributor.authorTiwari, Sudhanshuen_US
dc.contributor.authorSingh, Ajayen_US
dc.date.accessioned2009-05-28T15:54:28Z
dc.date.available2009-05-28T15:54:28Z
dc.date.issued2004-04-20en_US
dc.description.abstractActive compound oleandrin extracted from Nerium indicum (Lal Kaner) leaf has potent piscicidal activity. The piscicidal activity of oleandrin on freshwater fish C. punctatus was both time and dose dependent. Exposure to sub-lethal doses of oleandrin for 24hr and 96hr to fish caused significant alteration in the level of total protein, total free amino acid, nucleic acid, glycogen, pyruvate, lactate and enzyme protease, phosphatases, alanine aminotransferase, aspartate aminotransferase and acetylcholinesterase activity in liver and muscle tissues. The alterations in all the above biochemical parameters were also significantly time and dose dependent. The results show a significant recovery in all the above biochemical parameters, in both liver and muscle tissues of fish after the 7th day of the withdrawal of treatment. Toxicity persistence test of oleandrin on juvenile Labeo rohita shows that fish seed of common culturing carp can be released into rearing ponds after three days of oleandrin treatment. It supports the view that the oleandrin is safer and may be useful substitute of other piscicides for removing the unwanted freshwater fishes from aquaculture ponds.en_US
dc.description.affiliationNatural Product Laboratory, Department of Zoology, D.D.U. Gorakhpur University, Gorakhpur 273009, India.en_US
dc.identifier.citationTiwari S, Singh A. Toxic and sub-lethal effects of oleandrin on biochemical parameters of fresh water air breathing murrel, Channa punctatus (Bloch.). Indian Journal of Experimental Biology. 2004 Apr; 42(4): 413-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62566
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAcetylcholinesterase --metabolismen_US
dc.subject.meshAlanine Transaminase --metabolismen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAspartate Aminotransferases --metabolismen_US
dc.subject.meshCardenolides --chemistryen_US
dc.subject.meshCardiac Glycosides --chemistryen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshGlycogen --metabolismen_US
dc.subject.meshIndiaen_US
dc.subject.meshLactic Acid --metabolismen_US
dc.subject.meshLethal Dose 50en_US
dc.subject.meshLiver --chemistryen_US
dc.subject.meshMuscles --chemistryen_US
dc.subject.meshPerciformes --physiologyen_US
dc.subject.meshPlant Extracts --toxicityen_US
dc.subject.meshPlant Leaves --toxicityen_US
dc.subject.meshPyruvic Acid --metabolismen_US
dc.titleToxic and sub-lethal effects of oleandrin on biochemical parameters of fresh water air breathing murrel, Channa punctatus (Bloch.).en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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