D-dimer test: diagnostic role in clinical and sub-clinical DIC.

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dc.contributor.authorSaxena, Ren_US
dc.contributor.authorGupta, P Ken_US
dc.contributor.authorAhmed, Ren_US
dc.contributor.authorBatra, Vinitaen_US
dc.contributor.authorKumar, Sureshen_US
dc.date.accessioned2003-07-18en_US
dc.date.accessioned2009-05-29T13:36:33Z
dc.date.available2003-07-18en_US
dc.date.available2009-05-29T13:36:33Z
dc.date.issued2003-07-18en_US
dc.description.abstractD-dimer test is used as a diagnosis test for acute disseminated intravascular coagulation (DIC). This study was undertaken to find out its sensitivity and specificity in the diagnosis of acute DIC and its role in diagnosis of sub-clinical DIC, as there is limited data available on the subject. Of the 29 patients of clinically acute DIC, all had positive D-dimer test, and markedly prolonged PT, APTT and TT were seen in 24 (83%) of these patients. D-dimer test was found to be highly specific but less sensitive for the diagnosis of acute DIC. Of the 29 patients predisposed to sub-clinical DIC. D-dimer was positive is 26 (90%) patients and PT, APTT and TT were mildly prolonged in 11 patients. It is suggested that D-dimer positivity for the diagnoses of sub-clinical DIC need to be considered with caution and to be supplemented by other coagulation test including serial follow up with d-dimer and coagulation tests.en_US
dc.description.affiliationDepartment of Haematology, All India Institute of Medical Sciences, IRCH Building (1st Floor), Ansari Nagar, New Delhi. renusax@hotmail.comen_US
dc.identifier.citationSaxena R, Gupta PK, Ahmed R, Batra V, Kumar S. D-dimer test: diagnostic role in clinical and sub-clinical DIC. Indian Journal of Pathology & Microbiology. 2003 Jul; 46(3): 425-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/75831
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshDisseminated Intravascular Coagulation --blooden_US
dc.subject.meshFibrin Fibrinogen Degradation Products --analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshPartial Thromboplastin Timeen_US
dc.subject.meshPredictive Value of Testsen_US
dc.subject.meshProthrombin Timeen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshThrombin Timeen_US
dc.titleD-dimer test: diagnostic role in clinical and sub-clinical DIC.en_US
dc.typeJournal Articleen_US
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