Late inflammatory swelling by carrageenan in rat's subcutaneous neck tissue.

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dc.contributor.authorRao, T Sen_US
dc.contributor.authorMathur, Men_US
dc.contributor.authorBhide, N Ken_US
dc.date.accessioned1988-07-01en_US
dc.date.accessioned2009-06-01T08:04:26Z
dc.date.available1988-07-01en_US
dc.date.available2009-06-01T08:04:26Z
dc.date.issued1988-07-01en_US
dc.description.abstractWhen injected subcutaneously in the dorsum of neck in albino rats, carrageenan produced inflammatory swelling which reached peak after about 16 hr. The occurrence of the peak inflammatory swelling was delayed but not significantly reduced in severity by aspirin or indomethacin which were administered repeatedly. Phenylbutazone significantly reduced and dexamethasone almost completely inhibited it. In rat hind paw model, subplantar carrageenan injection produced peak inflammatory swelling after about 4 hr which was significantly reduced by all anti-inflammatory drugs mentioned above. It is interesting that an inflammagen when injected at different sites in the same species elicits responses which differ in the time course and drug responses.en_US
dc.description.affiliationDepartment of Pharmacology, All-India Institute of Medical Sciences, New Delhi.en_US
dc.identifier.citationRao TS, Mathur M, Bhide NK. Late inflammatory swelling by carrageenan in rat's subcutaneous neck tissue. Indian Journal of Physiology and Pharmacology. 1988 Jul-Sep; 32(3): 212-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/108638
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAspirin --pharmacologyen_US
dc.subject.meshCarrageenan --administration & dosageen_US
dc.subject.meshDexamethasone --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshIndomethacin --pharmacologyen_US
dc.subject.meshInflammation --chemically induceden_US
dc.subject.meshMaleen_US
dc.subject.meshNecken_US
dc.subject.meshPhenylbutazone --pharmacologyen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Inbred Strainsen_US
dc.subject.meshTime Factorsen_US
dc.titleLate inflammatory swelling by carrageenan in rat's subcutaneous neck tissue.en_US
dc.typeJournal Articleen_US
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