A Model Immunization Programme to Control Japanese Encephalitis in Viet Nam.
Loading...
Date
2015-03
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
In Viet Nam, an inactivated, mouse brain-derived vaccine for Japanese encephalitis (JE) has been given
exclusively to ≤5 years old children in 3 paediatric doses since 1997. However, JE incidence remained
high, especially among children aged 5-9 years. We conducted a model JE immunization programme to
assess the feasibility and impact of JE vaccine administered to 1-9 year(s) children in 3 standard-dose regimen:
paediatric doses for children aged <3 years and adult doses for those aged ≥3 years. Of the targeted
children, 96.2% were immunized with ≥2 doses of the vaccine. Compared to the national immunization
programme, JE incidence rate declined sharply in districts with the model programme (11.32 to 0.87 per
100,000 in pre- versus post-vaccination period). The rate of reduction was most significant in the 5-9 years
age-group. We recommend a policy change to include 5-9 years old children in the catch-up immunization
campaign and administer a 4th dose to those aged 5-9 years, who had received 3 doses of the vaccine
during the first 2-3 years of life.
Description
Keywords
Demonstration project, Effectiveness study, Immunization, Japanese encephalitis, Vaccines
Citation
Yen Nguyen Thu, Liu Wei, Hanh Hoang Duc, Chang Na Yoon, Duong Tran Nhu, Gibbons Robert V, Marks Florian, Thu Nghiem Anh, Hong Nguyen Minh, Park Jin Kyung, Tuan Pham Anh, Nisalak Ananda, Clemens John D, Xu Zhi-yi. A Model Immunization Programme to Control Japanese Encephalitis in Viet Nam. Journal of Health, Population and Nutrition. 2015 Mar; 33(1): 207-213.