Retinoblastoma or Neuroblastoma: an imaging polemic issues

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dc.contributor.authorGiri, Winda W.en_US
dc.contributor.authorAnandasari, Yulien_US
dc.contributor.authorMargiani, Ni Nyomanen_US
dc.contributor.authorAyusta, Dwija Putraen_US
dc.contributor.authorAriawati, Ketuten_US
dc.contributor.authorDewi, Sri Mahendraen_US
dc.date.accessioned2020-11-18T10:00:35Z
dc.date.available2020-11-18T10:00:35Z
dc.date.issued2020-02
dc.description.abstractBoth retinoblastoma and neuroblastoma are common childhood malignancy, which classified as malignant round cell tumors, but have different diagnostic, therapeutic, prognostic criteria and metastases pattern. A case was evaluated with an imaging examination resembled neuroblastoma metastatic process but was diagnosed as retinoblastoma. A 2-years-old boy came with chief complaint swollen right eye. Prior history was itchy and increasingly swollen right eye, decreased vision and gradually increases pain. There was no sign of leukocoria. Histopathology result confirmed malignant round cell tumor. Axial contrast-enhanced head CT image, depicted right intra orbital mass, 1.9x2x1.8 cm in size as well as mass in the right frontoparietal region which pushed the right frontal lobe, accompanied by erosion and periosteal reaction in the surrounding bone with meningeal and soft tissue involvement. In this case, although there was no leukocoria as the diagnostic criteria for retinoblastoma, we still found intraorbital and pineal body mass also malignancies in several long bones. The diagnosis of trilateral retinoblastoma has been established followed by retinoblastoma’s chemotherapy regiment, which showed good response, in spite of discrepancy in retinoblastoma’s metastases pattern. A complete systemic workup includes CT scan examination needs to be perform in order to help the clinicians determine the diagnosis of orbital mass with malignant round cell histopathology.en_US
dc.identifier.affiliationsDepartment of Radiology, Faculty of Medicine, Universitas Udayana, Sanglah General Hospital, Bali, Indonesiaen_US
dc.identifier.affiliationsDepartment of Pediatric Hemato-Oncology, Faculty of Medicine, Universitas Udayana, Sanglah General Hospital, Bali, Indonesiaen_US
dc.identifier.affiliationsDepartment of Histopathology, Faculty of Medicine, Universitas Udayana, Sanglah General Hospital, Bali, Indonesiaen_US
dc.identifier.citationGiri Winda W., Anandasari Yuli, Margiani Ni Nyoman, Ayusta Dwija Putra, Ariawati Ketut, Dewi Sri Mahendra. Retinoblastoma or Neuroblastoma: an imaging polemic issues. International Journal of Research in Medical Sciences. 2020 Feb; 8(2): 771-776en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/211996
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20200273en_US
dc.subjectHead computerized tomographyen_US
dc.subjectNeuroblastomaen_US
dc.subjectRetinoblastomaen_US
dc.titleRetinoblastoma or Neuroblastoma: an imaging polemic issuesen_US
dc.typeJournal Articleen_US
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