Role of carotid intima-media thickness in assessment of atherosclerosis: an autopsy study.

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dc.contributor.authorJashnani, Kusum Den_US
dc.contributor.authorKulkarni, Rohit Ren_US
dc.contributor.authorDeshpande, Jaya Ren_US
dc.date.accessioned2005-07-15en_US
dc.date.accessioned2009-05-27T04:18:13Z
dc.date.available2005-07-15en_US
dc.date.available2009-05-27T04:18:13Z
dc.date.issued2005-07-15en_US
dc.description.abstractBACKGROUND: The non-invasive technique of measuring carotid artery intima-media thickness has generated considerable interest as a marker of atherosclerosis, particularly in predicting clinical coronary events and coronary artery disease. In the present study, a postmortem comparative analysis of intima-media thickness of carotid artery with coronary artery atherosclerosis has been carried out. To date no such morphological tissue studies are available from our country. METHODS AND RESULTS: Right and left common carotid arteries with their branches were removed at postmortem in 40 cases with history of diabetes, hypertension or both. Intima-media thickness was measured and compared with coronary artery atherosclerosis. There were 10 control postmortem cases without history of diabetes or hypertension. Common carotid artery and internal carotid artery intima-media thickness were found to be good predictors of coronary events. There was also significant correlation (by Pearson's correlation formula) between the carotid artery intima-media thickness and the percentage of block in the coronary arteries. CONCLUSIONS: Internal carotid artery along with common carotid artery intima-media thickness measurement is a good predictor of coronary artery disease. However, carotid artery intima-media thickness has no bearing on the status of collateral circulation of the coronary arteries.en_US
dc.description.affiliationDepartment of Pathology, TN Medical College and BYL Nair Ch Hospital, Mumbai. kusumjash@hotmail.comen_US
dc.identifier.citationJashnani KD, Kulkarni RR, Deshpande JR. Role of carotid intima-media thickness in assessment of atherosclerosis: an autopsy study. Indian Heart Journal. 2005 Jul-Aug; 57(4): 319-23en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/3084
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAgeden_US
dc.subject.meshCarotid Artery, Common --pathologyen_US
dc.subject.meshCarotid Artery, Internal --pathologyen_US
dc.subject.meshCoronary Artery Disease --pathologyen_US
dc.subject.meshCoronary Vessels --pathologyen_US
dc.subject.meshDiabetes Mellitus --pathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypertension --pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPredictive Value of Testsen_US
dc.subject.meshTunica Intima --pathologyen_US
dc.subject.meshTunica Media --pathologyen_US
dc.titleRole of carotid intima-media thickness in assessment of atherosclerosis: an autopsy study.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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