Advances in pharmacological strategies for the prevention of cataract development.

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dc.contributor.authorGupta, S Ken_US
dc.contributor.authorSelvan, V Kalaien_US
dc.contributor.authorAgrawal, S Sen_US
dc.contributor.authorSaxena, Rohiten_US
dc.date.accessioned2009-05-23en_US
dc.date.accessioned2009-05-29T10:14:15Z
dc.date.available2009-05-23en_US
dc.date.available2009-05-29T10:14:15Z
dc.date.issued2009-05-23en_US
dc.description.abstractCataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of putative anticataract agents comes from a variety of approaches, ranging from laboratory experiments, both in vitro and in vivo , to epidemiological studies in patients. This review deals with the various mechanisms, and possible pharmacological interventions for the prevention of cataract. The article also reviews research on potential anticataractous agents, including aldose reductase inhibitors, glutathione boosters, antiglycating agents, vitamins and various drugs from indigenous sources.en_US
dc.description.affiliationDelhi Institute of Pharmaceutical Sciences and Research, Sector 3, Pushp Vihar, New Delhi-110 017, India. skgup@hotmail.com.en_US
dc.identifier.citationGupta SK, Selvan VK, Agrawal SS, Saxena R. Advances in pharmacological strategies for the prevention of cataract development. Indian Journal of Ophthalmology. 2009 May-Jun; 57(3): 175-83en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/72464
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.source.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683438/en_US
dc.subject.meshAldehyde Reductase --antagonists & inhibitors
dc.subject.meshAntioxidants --administration & dosage
dc.subject.meshCataract --etiology
dc.subject.meshCataract --prevention & control
dc.subject.meshGlutathione --administration & dosage
dc.subject.meshHumans
dc.subject.meshPharmaceutical Preparations
dc.subject.meshRisk Factors
dc.subject.meshVitamins --administration & dosage
dc.titleAdvances in pharmacological strategies for the prevention of cataract development.en_US
dc.typeJournal Articleen_US
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