Biocatalytic and electrochemical reduction of selected phenyl alkanones with antibacterial activity of the corresponding phenyl alkanols.

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dc.contributor.authorSharma, Archana
dc.contributor.authorOjha, Poonam
dc.contributor.authorVerma, P S
dc.contributor.authorSharma, I K
dc.date.accessioned2015-08-20T05:28:55Z
dc.date.available2015-08-20T05:28:55Z
dc.date.issued2011-07
dc.description.abstractThis paper reports the production of some phenyl alkanols by the biocatalytic and electrochemical reduction of selected Phenyl alkanones viz. Propiophenone, Butyrophenone, and Valerophenone. Baker‘s yeast was used in its free as well as immobilized form for biocatalytic reduction. Substrates showed the higher conversion rate when the cells were used in immobilized form. The electrochemical behavior of substrates was investigated cyclic voltammetrically to explore electrochemical reduction as alternative synthetic route for the preparation of alcohols. Results obtained from cyclic voltammetric studies were used for establishing optimum conditions for electrochemical reduction which was then carried out galvanostatically using economically viable stainless steel (SS-316) electrodes. The reduction products were isolated and purified by chromatographic techniques and characterized on the basis of spectral analysis. The products thus obtained also exhibited significant antibacterial activity against four strains of bacteria viz. Staphylococcus aureus, Enterococcus faecaulis, Escherichia coli, Pseudomonas aeruginosa.en_US
dc.identifier.citationSharma Archana, Ojha Poonam, Verma P S, Sharma I K. Biocatalytic and electrochemical reduction of selected phenyl alkanones with antibacterial activity of the corresponding phenyl alkanols. International Journal of Applied Biology and Pharmaceutical Technology. 2011 Jul-Sept; 2(3): 277-286.en_US
dc.identifier.issn0976-4550
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/162131
dc.language.isoenen_US
dc.source.urihttps://www.ijabpt.com/Details.aspx?fid=379en_US
dc.subjectPropiophenoneen_US
dc.subjectButyrophenoneen_US
dc.subjectValerophenoneen_US
dc.subjectBaker‘s yeast (BY)en_US
dc.subjectBiocatalytic reductionen_US
dc.subjectImmobilized Baker’s yeast (ImBY)en_US
dc.subjectAntibacterial Activityen_US
dc.subjectCyclic Voltammetryen_US
dc.subjectStainless Steel Electrode (SS-316)en_US
dc.titleBiocatalytic and electrochemical reduction of selected phenyl alkanones with antibacterial activity of the corresponding phenyl alkanols.en_US
dc.typeArticleen_US
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