Comparative Morphological and Morphometrical Analysis of Atrio-Ventricular Valves of Human and Porcine

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dc.contributor.authorS, Supadevien_US
dc.contributor.authorVijaykumar, K.en_US
dc.contributor.authorS, Supasakthien_US
dc.contributor.authorN, Manimozhianen_US
dc.date.accessioned2023-08-25T06:45:33Z
dc.date.available2023-08-25T06:45:33Z
dc.date.issued2023-03
dc.description.abstractThere is increased incidence of valvular heart diseases in recent years due to life style modifications. The mortality rates in valvular diseases are kept in pace using various modalities of treatments. One such lifesaving treatment is valve replacement surgeries. These are done by using mechanical valve prosthesis or tissue grafts. The tissue valves prosthesis, harvested from porcine heart are called as xenograft and are increasingly used in valve repair and replacement surgeries. In the present scenario, there is a smaller number of systematically analysed literatures available on the comparative anatomy of human and porcine heart valves. Hence this study was carried out to acquire knowledge and to put forth some points to future research works on heart valves. In this study, 20 formalin fixed porcine and human hearts were procured from slaughter house and cadavers respectively. The morphology and morphometry of tricuspid valve and mitral valve was observed and analysed using spss software 20 version. All the dependent variables were compared using student t test and independent sample test. The results were tabulated and compared. It was observed that the tricuspid and the mitral valve of the porcine resembles the corresponding human heart valves in morphology and morphometry and their values were coinciding to their maximum. The porcine valve resembles human heart valves in morphology and it can be used in designing valve substitutes in replacement surgeries. Porcine valve can also be used as bio-prosthesis by matching the morphometry and by reducing the geometrical difference to their minimum by using any interventional radiology.en_US
dc.identifier.affiliationsAssistant professor, Sri Muthukumaran Medical College and Research Institute, Chennai, Tamilnadu, Indiaen_US
dc.identifier.affiliationsAssistant professor of Anatomy, Symbiosis Medical College for Women (SMCW), Symbiosis International (Deemed) University (SIU), lavale, Pune, Indiaen_US
dc.identifier.affiliationsConsultant pathologist, Kongunadu hospital, Coimbatore, Tamilnadu, Indiaen_US
dc.identifier.affiliationsConsultant paediatrician, Mrithun child care clinic, Chennai, Tamilnadu, India.en_US
dc.identifier.citationS Supadevi, Vijaykumar K., S Supasakthi, N Manimozhian. Comparative Morphological and Morphometrical Analysis of Atrio-Ventricular Valves of Human and Porcine. International Journal of Anatomy and Research. 2023 Mar; 11(1): 8559-8563en_US
dc.identifier.issn2321-4287
dc.identifier.issn2321-8967
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/225624
dc.languageenen_US
dc.publisherIMD Research Publicationsen_US
dc.relation.issuenumber1en_US
dc.relation.volume11en_US
dc.source.urihttps://dx.doi.org/10.16965/ijar.2022.287en_US
dc.subjectTissue Graften_US
dc.subjectPorcineen_US
dc.subjectTricuspid Valveen_US
dc.subjectMitral Valveen_US
dc.subjectMorphology And Morphometry.en_US
dc.titleComparative Morphological and Morphometrical Analysis of Atrio-Ventricular Valves of Human and Porcineen_US
dc.typeJournal Articleen_US
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