Quality of life after peptic perforation.

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dc.contributor.authorJoneja, Jaspreet Sen_US
dc.contributor.authorSharma, D Ben_US
dc.contributor.authorSharma, Dhananjayaen_US
dc.contributor.authorRaina, V Ken_US
dc.date.accessioned2004-03-08en_US
dc.date.accessioned2009-05-31T01:02:10Z
dc.date.available2004-03-08en_US
dc.date.available2009-05-31T01:02:10Z
dc.date.issued2004-03-08en_US
dc.description.abstractAIM OF STUDY: Quality of life (QOL) as outcome during treatment of acid peptic disease has been studied, but, peptic perforation, which is the commonest complication of acid peptic disease, has not been studied in the light of QOL outcome. The present-study addresses the important issue of QOL after peptic perforations. METHODS: This prospective study was carried on 51 adult consecutive survivors of peptic perforation managed in Gastrointestinal Surgery Unit, Department of Surgery, Government NSCB Medical College and Hospital, Jabalpur (MP) India. These underwent exploratory laparotomy with repair of perforation, and subsequently were discharged on anti-ulcer therapy (Pantoprazole 40 mg once a day) for 6 weeks. The instrument chosen to study their QOL was gastrointestinal quality of life index (GIQLI). Patients were assessed before they underwent surgery and 3 months and 6 months after operation. RESULTS: The overall GIQLI score (t = 20.1, p < 0.00 at 3 months; t = 8.2, p < 0.001 at 6 months) as well as its G I core (t = 14.5, p < 0.001 at 3 months; t = 7.3, p < 0.001 at 6 months), G I disease specific (t = 12.9, p < 0.001 at 3 months; t = 2.6, p < 0.02 at 6 months), psychological (t = 15.4, p < 0.001 at 3 months; t = 3.5, p < 0.001 at 6 months) and physical and social components (t = 10.9, p < 0.001 at 3 months; t = 4.2, p < 0.001 at 6 months) significantly increased over 3 and 6 months of follow-up, reflecting improvement in quality of life as perceived by the patients. Variations in the pattern of recovery, based on age and gender were not seen in the present study. CONCLUSION: Peptic perforation does not result in any long lasting impairment of QOL and the QOL improves to near normal in 6 months time after the perforation.en_US
dc.description.affiliationGI Surgery Unit, Department of Surgery, NSCB Government Medical College and Allied Hospitals, Jabalpur (MP), India 482 003.en_US
dc.identifier.citationJoneja JS, Sharma DB, Sharma D, Raina VK. Quality of life after peptic perforation. Journal of the Association of Physicians of India. 2004 Mar; 52(): 207-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/91824
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.mesh2-Pyridinylmethylsulfinylbenzimidazolesen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshAnti-Ulcer Agents --therapeutic useen_US
dc.subject.meshBenzimidazoles --therapeutic useen_US
dc.subject.meshDigestive System Surgical Proceduresen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOmeprazole --analogs & derivativesen_US
dc.subject.meshOutcome Assessment (Health Care)en_US
dc.subject.meshPeptic Ulcer Perforation --drug therapyen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshQuality of Lifeen_US
dc.subject.meshQuestionnairesen_US
dc.subject.meshSickness Impact Profileen_US
dc.subject.meshSulfoxides --therapeutic useen_US
dc.titleQuality of life after peptic perforation.en_US
dc.typeJournal Articleen_US
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